STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
EHQ02255.1Cytoplasmic peptidoglycan synthetase domain protein; PFAM: Mur ligase family, catalytic domain; Mur ligase family, glutamate ligase domain; Mur ligase middle domain; COGs: COG0773 UDP-N-acetylmuramate-alanine ligase; InterPro IPR000713:IPR013221:IPR004101; KEGG: lan:Lacal_1516 UDP-N-acetylmuramate--L-alanine ligase; PFAM: Mur ligase, N-terminal; Mur ligase, central; Mur ligase, C-terminal; SPTR: Cytoplasmic peptidoglycan synthetase domain protein. (451 aa)    
Predicted Functional Partners:
murD
UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
 
 0.912
EHQ03257.1
Cyanophycin synthetase; PFAM: RimK-like ATP-grasp domain; Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: cyanophycin synthetase; COGs: COG0769 UDP-N-acetylmuramyl tripeptide synthase; InterPro IPR013651:IPR013221:IPR004101:IPR011810; KEGG: gfo:GFO_0745 cyanophycin synthetase; PFAM: Mur ligase, central; ATP-grasp fold, RimK-type; Mur ligase, C-terminal; SPTR: Cyanophycin synthetase; TIGRFAM: Cyanophycin synthetase.
  
 
 0.908
EHQ03258.1
Cyanophycin synthetase; PFAM: RimK-like ATP-grasp domain; Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: cyanophycin synthetase; COGs: COG0769 UDP-N-acetylmuramyl tripeptide synthase; InterPro IPR013651:IPR013221:IPR004101:IPR011810; KEGG: gfo:GFO_0745 cyanophycin synthetase; PFAM: Mur ligase, central; ATP-grasp fold, RimK-type; Mur ligase, C-terminal; SPTR: Cyanophycin synthetase; TIGRFAM: Cyanophycin synthetase; manually curated.
  
 
 0.908
murF
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
 
 
 0.902
ddl
D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
 
 0.885
murG
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
 
 0.864
murE
UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.
 
 0.741
EHQ01764.1
Hypothetical protein; PFAM: CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase; KEGG: fjo:Fjoh_0303 hypothetical protein; SPTR: Putative uncharacterized protein.
  
 
 0.731
EHQ02158.1
KEGG: gfo:GFO_2766 FtsQ-like cell division protein; SPTR: FtsQ-like cell division protein.
  
  
 0.726
mraY
Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
 
  
 0.694
Your Current Organism:
Gillisia limnaea
NCBI taxonomy Id: 865937
Other names: G. limnaea DSM 15749, Gillisia limnaea DSM 15749, Gillisia limnaea R-8282, Gillisia limnaea str. DSM 15749, Gillisia limnaea strain DSM 15749
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