STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHQ02647.1PfkB domain protein; PFAM: pfkB family carbohydrate kinase; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: zpr:ZPR_0275 PfkB family carbohydrate kinase; PFAM: Carbohydrate/purine kinase; SPTR: PfkB family carbohydrate kinase. (312 aa)    
Predicted Functional Partners:
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
 0.812
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
 
 0.796
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
 0.704
EHQ02648.1
PFAM: Glutamine amidotransferases class-II; COGs: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; InterPro IPR000583; KEGG: zpr:ZPR_0274 amidophosphoribosyltransferase; PFAM: Glutamine amidotransferase, class-II; SPTR: Amidophosphoribosyltransferase.
  
 
 0.691
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 0.660
EHQ02706.1
PFAM: Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase; GlcNAc-PI de-N-acetylase; TIGRFAM: glucosamine-6-phosphate isomerase; COGs: COG0363 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase; InterPro IPR018322:IPR006148:IPR003737; KEGG: zpr:ZPR_4699 glucosamine-6-phosphate deaminase; PFAM: Glucosamine/galactosamine-6-phosphate isomerase; N-acetylglucosaminyl phosphatidylinositol deacetylase; SPTR: Glucosamine-6-phosphate deaminase; TIGRFAM: Glucosamine-6-phosphate isomerase, subgroup.
  
 
 0.638
EHQ03192.1
PFAM: Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase; GlcNAc-PI de-N-acetylase; TIGRFAM: glucosamine-6-phosphate isomerase; COGs: COG0363 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase; InterPro IPR006148:IPR003737:IPR018322; KEGG: zpr:ZPR_4699 glucosamine-6-phosphate deaminase; PFAM: Glucosamine/galactosamine-6-phosphate isomerase; N-acetylglucosaminyl phosphatidylinositol deacetylase; SPTR: Glucosamine-6-phosphate deaminase; TIGRFAM: Glucosamine-6-phosphate isomerase, subgroup.
  
 
 0.638
EHQ02012.1
PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase; COGs: COG0036 Pentose-5-phosphate-3-epimerase; InterPro IPR000056; KEGG: gfo:GFO_0377 ribulose-phosphate 3-epimerase; PFAM: Ribulose-phosphate 3-epimerase; SPTR: Ribulose-phosphate 3-epimerase; TIGRFAM: Ribulose-phosphate 3-epimerase.
  
 0.622
hisA
1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino) imidazole-4-carboxamide isomerase; PFAM: Histidine biosynthesis protein; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; COGs: COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase; HAMAP:1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; InterPro IPR006063:IPR006062; KEGG: zpr:ZPR_2392 phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide(ProFAR) isomerase; PFAM: Histidine biosynthes [...]
  
    0.608
purN
Formyltetrahydrofolate-dependent phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
     
 0.587
Your Current Organism:
Gillisia limnaea
NCBI taxonomy Id: 865937
Other names: G. limnaea DSM 15749, Gillisia limnaea DSM 15749, Gillisia limnaea R-8282, Gillisia limnaea str. DSM 15749, Gillisia limnaea strain DSM 15749
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