STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHQ02648.1PFAM: Glutamine amidotransferases class-II; COGs: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; InterPro IPR000583; KEGG: zpr:ZPR_0274 amidophosphoribosyltransferase; PFAM: Glutamine amidotransferase, class-II; SPTR: Amidophosphoribosyltransferase. (632 aa)    
Predicted Functional Partners:
purL
AIR synthase related protein domain protein; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
 
 0.999
purD
Phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, C domain; TIGRFAM: phosphoribosylamine--glycine ligase; COGs: COG0151 Phosphoribosylamine-glycine ligase; HAMAP: Phosphoribosylglycinamide synthetase; InterPro IPR000115:IPR020562:IPR020561:IPR020560; KEGG: gfo:GFO_3282 phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthe [...]
 0.998
purN
Formyltetrahydrofolate-dependent phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
 
 0.984
EHQ03577.1
PFAM: AIR synthase related protein, C-terminal domain; COGs: COG0150 Phosphoribosylaminoimidazole (AIR) synthetase; InterPro IPR010918; KEGG: zpr:ZPR_3153 phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein, C-terminal; SPTR: Phosphoribosylformylglycinamidine cyclo-ligase.
 
 
 0.984
purH
PFAM: AICARFT/IMPCHase bienzyme; MGS-like domain; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; COGs: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); InterPro IPR013982:IPR011607:IPR002695; KEGG: zpr:ZPR_0662 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: AICARFT/IMPCHase bienzyme, formylation region; MGS-like; SMART: AICARFT/IMPCHase bienzyme, formylation region; SPTR: Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cycloh [...]
 
 0.974
purC
PFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; COGs: COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; HAMAP: Phosphoribosylaminoimidazole-succinocarboxamide synthase; InterPro IPR001636; KEGG: lan:Lacal_2786 phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase; SPTR: Phosphoribosylaminoimidazolesuccinocarboxamide synthase.
 
 0.972
EHQ04115.1
Carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; TIGRFAM: carbamoyl-phosphate synthase, large subunit; COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterPro IPR005481:IPR005479:IPR005480:IPR006275; KEGG: zpr:ZPR_2048 carbamoyl-phosphate synthase large subunit; PFAM: Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthase, large subunit, N-te [...]
 
 
 0.962
EHQ04134.1
PFAM: Lyase; Adenylosuccinate lyase C-terminal; TIGRFAM: adenylosuccinate lyase; COGs: COG0015 Adenylosuccinate lyase; InterPro IPR000362:IPR013539:IPR004769; KEGG: cao:Celal_0053 adenylosuccinate lyase; PFAM: Adenylosuccinate lyase C-terminal; Fumarate lyase; SPTR: Adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
 
 
 0.961
carA
PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit; COGs: COG0505 Carbamoylphosphate synthase small subunit; InterPro IPR002474:IPR000991:IPR006274; KEGG: zpr:ZPR_3848 carbamoyl phosphate synthase small subunit; PFAM: Glutamine amidotransferase class-I, C-terminal; Carbamoyl phosphate synthase, small subunit, N-terminal; SPTR: Carbamoyl phosphate synthase small subunit; TIGRFAM: Carbamoyl phosphate synthase, small subunit; Belongs to the CarA family.
 
 
 0.952
purE
5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
 
 
 0.950
Your Current Organism:
Gillisia limnaea
NCBI taxonomy Id: 865937
Other names: G. limnaea DSM 15749, Gillisia limnaea DSM 15749, Gillisia limnaea R-8282, Gillisia limnaea str. DSM 15749, Gillisia limnaea strain DSM 15749
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.