STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
uvrCExcinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (614 aa)    
Predicted Functional Partners:
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
 0.991
EHQ04292.1
Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
 
 0.895
EHQ01453.1
Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
 
 0.891
EHQ03151.1
Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
 
 0.880
EHQ03108.1
PFAM: PHP domain; Bacterial DNA polymerase III alpha subunit; Exonuclease; TIGRFAM: DNA-directed DNA polymerase III (polc); COGs: COG0587 DNA polymerase III alpha subunit; InterProIPR004805:IPR006055:IPR003141:IPR013520:IPR 004013:IPR011708:IPR004365; KEGG: zpr:ZPR_4431 DNA polymerase III subunit alpha-1; PFAM: Bacterial DNA polymerase III, alpha subunit; PHP, C-terminal; Exonuclease, RNase T/DNA polymerase III; Nucleic acid binding, OB-fold, tRNA/helicase-type; SMART: Exonuclease; Polymerase/histidinol phosphatase, N-terminal; SPTR: DNA polymerase III subunit alpha-1; TIGRFAM: DNA pol [...]
 
  
 0.829
EHQ02849.1
PFAM: Patatin-like phospholipase; COGs: COG1752 esterase of the alpha-beta hydrolase superfamily; InterPro IPR002641:IPR010827; KEGG: gfo:GFO_3172 patatin-like phospholipase; PFAM: Patatin; Surface antigen variable number; SPTR: Patatin-like phospholipase.
       0.819
EHQ03770.1
PFAM: UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR000212; KEGG: gfo:GFO_2323 PcrA-like UvrD/Rep family ATP-dependent DNA helicase; PFAM: DNA helicase, UvrD/REP type; SPTR: PcrA-like UvrD/Rep family ATP-dependent DNA helicase.
 
  
 0.731
recR
DNA replication and repair protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.
 
 
 
 0.595
EHQ02844.1
PFAM: 5-formyltetrahydrofolate cyclo-ligase family; TIGRFAM: 5,10-methenyltetrahydrofolate synthetase; COGs: COG0212 5-formyltetrahydrofolate cyclo-ligase; InterPro IPR002698; KEGG: zpr:ZPR_0180 5-formyltetrahydrofolate cyclo-ligase; PFAM: 5-formyltetrahydrofolate cyclo-ligase; SPTR: 5-formyltetrahydrofolate cyclo-ligase; TIGRFAM: 5-formyltetrahydrofolate cyclo-ligase.
       0.571
EHQ02845.1
PFAM: Succinylglutamate desuccinylase / Aspartoacylase family; COGs: COG3608 deacylase; InterPro IPR007036; KEGG: gfo:GFO_3176 succinylglutamate desuccinylase / aspartoacylase family protein; PFAM: Succinylglutamate desuccinylase/aspartoacylase; SPTR: Succinylglutamate desuccinylase / aspartoacylase family protein.
       0.551
Your Current Organism:
Gillisia limnaea
NCBI taxonomy Id: 865937
Other names: G. limnaea DSM 15749, Gillisia limnaea DSM 15749, Gillisia limnaea R-8282, Gillisia limnaea str. DSM 15749, Gillisia limnaea strain DSM 15749
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