STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
EHQ03042.1Cl- channel voltage-gated family protein; PFAM: CBS domain; Voltage gated chloride channel; COGs: COG0038 Chloride channel protein EriC; InterPro IPR001807:IPR000644; KEGG: gfo:GFO_3091 voltage gated chloride channel; PFAM: Chloride channel, voltage gated; Cystathionine beta-synthase, core; SPTR: Voltage gated chloride channel. (596 aa)    
Predicted Functional Partners:
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
 
 0.874
EHQ03041.1
KEGG: gfo:GFO_3092 membrane protein; SPTR: Membrane protein.
       0.799
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
 
 0.759
EHQ03667.1
KpsF/GutQ family protein; PFAM: CBS domain; SIS domain; TIGRFAM: KpsF/GutQ family protein; COGs: COG0794 sugar phosphate isomerase involved in capsule formation; InterPro IPR004800:IPR001347:IPR000644; KEGG: cat:CA2559_12348 sugar isomerase, KpsF/GutQ family protein; PFAM: Sugar isomerase (SIS); Cystathionine beta-synthase, core; SPTR: Sugar isomerase, KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ; Belongs to the SIS family. GutQ/KpsF subfamily.
    
  0.752
aspS
aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
       0.640
ribB
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
  
 
 0.639
atpH
ATP synthase F1 subcomplex delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
  
 
  0.556
surE
Multifunctional protein surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
   
  0.553
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
    
 0.535
EHQ03508.1
Histidine kinase; PFAM: Y_Y_Y domain; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Two component regulator propeller; COGs: COG0642 Signal transduction histidine kinase; InterProIPR011110:IPR011123:IPR003594:IPR001789:IPR 018060; KEGG: gfo:GFO_2999 two-component system sensor histidine kinase/response regulator hybrid; PFAM: ATP-binding region, ATPase-like; Two component regulator three Y; Two component regulator propeller; Signal transduction response regulator, receiver region; SMART: ATP-binding region, ATPase-like; Signal transduction [...]
    
  0.529
Your Current Organism:
Gillisia limnaea
NCBI taxonomy Id: 865937
Other names: G. limnaea DSM 15749, Gillisia limnaea DSM 15749, Gillisia limnaea R-8282, Gillisia limnaea str. DSM 15749, Gillisia limnaea strain DSM 15749
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