STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHQ03091.1Integral membrane sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG5002 Signal transduction histidine kinase; InterPro IPR003661:IPR003594; KEGG: gfo:GFO_0119 two-component system sensor histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SPTR: Two-component system [...] (365 aa)    
Predicted Functional Partners:
EHQ03090.1
Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: zpr:ZPR_0499 two-component system response regulator; PFAM: Signal transduction response regulator, receiver region; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver region; SPTR: Two-component system response regulator.
 0.998
EHQ01520.1
Adenylate/guanylate cyclase with GAF sensor(s); PFAM: Adenylate and Guanylate cyclase catalytic domain; Protein kinase domain; GAF domain; COGs: COG3899 ATPase; InterPro IPR002290:IPR001054:IPR017442:IPR003018; KEGG: ter:Tery_2857 adenylate/guanylate cyclase; PFAM: Adenylyl cyclase class-3/4/guanylyl cyclase; Serine/threonine-protein kinase-like domain; GAF; SMART: Serine/threonine-protein kinase domain; Adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Serine/threonine kinase with two-component sensor domain.
 
 0.986
EHQ04038.1
MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor; PFAM: CheB methylesterase; CheR methyltransferase, SAM binding domain; CheR methyltransferase, all-alpha domain; PAS fold; COGs: COG1352 Methylase of chemotaxis methyl-accepting protein; InterPro IPR000673:IPR000780:IPR013656:IPR000014; KEGG: dba:Dbac_2162 MCP methyltransferase/methylesterase CheR/CheB; PFAM: Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase; MCP methyltransferase, CheR-type; PAS fold-4; SMART: MCP methyltransferase, CheR-type; SPTR: MCP methyltransferase/methylester [...]
 
 
 0.985
EHQ02962.1
PFAM: Adenylate and Guanylate cyclase catalytic domain; Response regulator receiver domain; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001789:IPR001054; KEGG: lby:Lbys_1798 adenylate/guanylate cyclase; PFAM: Signal transduction response regulator, receiver region; Adenylyl cyclase class-3/4/guanylyl cyclase; SMART: Signal transduction response regulator, receiver region; Adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Serine/threonine protein kinase/response regulator/adenylate cyclase.
 0.976
EHQ02699.1
Multi-sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; CHASE3 domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR001610:IPR003661:IPR003594:IPR 007891:IPR013655:IPR013656; KEGG: fba:FIC_01552 two-component system sensor histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; CHASE3; PAS fold-3; PAS fold-4; SMART: ATP-binding region, ATPa [...]
 
0.972
EHQ03686.1
Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: gfo:GFO_0658 two-component system response regulator; PFAM: Signal transduction response regulator, receiver region; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver region; SPTR: Two-component system response regulator.
 0.966
EHQ02925.1
PFAM: Response regulator receiver domain; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789; KEGG: gfo:GFO_1628 response regulator receiver domain-containing protein; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; SPTR: Protein containing response regulator receiver domain.
 
 0.963
EHQ04071.1
Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: cao:Celal_2320 two component transcriptional regulator, winged helix family; PFAM: Signal transduction response regulator, receiver region; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver region; SPTR: Two component transcription [...]
 0.963
EHQ02926.1
PFAM: Response regulator receiver domain; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789; KEGG: gfo:GFO_1686 response regulator receiver domain-containing protein; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; SPTR: Protein containing response regulator receiver domain.
 
 0.961
EHQ02924.1
PFAM: CheB methylesterase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; CheR methyltransferase, SAM binding domain; His Kinase A (phosphoacceptor) domain; CheR methyltransferase, all-alpha domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG1352 Methylase of chemotaxis methyl-accepting protein; InterProIPR000014:IPR000780:IPR001610:IPR003661:IPR 003594:IPR000673:IPR013767:IPR013656:IPR013655; KEGG: gfo:GFO_1684 two-component system sensor histidine kinase/methyl-esterase/transferase hybrid; PFAM: ATP-binding region, ATPase-like; PAS fold-3; Signal transduction response re [...]
 
 
0.955
Your Current Organism:
Gillisia limnaea
NCBI taxonomy Id: 865937
Other names: G. limnaea DSM 15749, Gillisia limnaea DSM 15749, Gillisia limnaea R-8282, Gillisia limnaea str. DSM 15749, Gillisia limnaea strain DSM 15749
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