STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
EHQ03246.1Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (413 aa)    
Predicted Functional Partners:
EHQ03701.1
Oxygen-independent coproporphyrinogen III oxidase; PFAM: Radical SAM superfamily; HemN C-terminal region; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; COGs: COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductase; InterPro IPR004558:IPR007197:IPR010723:IPR006638; KEGG: fbc:FB2170_03835 coproporphyrinogen III oxidase; PFAM: HemN, C-terminal; Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Coproporphyrinogen III oxidase; TIGRFAM: Oxygen-independent coproporphyrinogen III oxidase HemN; Belongs to the anaerobic coproporphyrinogen-III oxidase family.
  
  
 
0.867
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
  
 
 0.865
EHQ02571.1
PFAM: Coproporphyrinogen III oxidase; COGs: COG0408 Coproporphyrinogen III oxidase; InterPro IPR001260; KEGG: cao:Celal_1636 coproporphyrinogen oxidase; PFAM: Coproporphyrinogen III oxidase; SPTR: Coproporphyrinogen oxidase.
    
 0.865
EHQ02561.1
PFAM: Uncharacterised protein family (UPF0093); TIGRFAM: TIGR00701 family protein; COGs: COG1981 membrane protein; InterPro IPR005265; KEGG: gfo:GFO_3217 membrane protein, UPF0093; PFAM: Uncharacterised protein family UPF0093; SPTR: Membrane protein, UPF0093.
    
 0.862
EHQ03592.1
PFAM: Cytochrome C oxidase, mono-heme subunit/FixO; Cytochrome C and Quinol oxidase polypeptide I; TIGRFAM: cytochrome c oxidase, cbb3-type, subunit II; cytochrome c oxidase, cbb3-type, subunit I; COGs: COG3278 Cbb3-type cytochrome oxidase subunit 1; InterPro IPR004677:IPR003468:IPR000883; KEGG: cly:Celly_2050 cytochrome c oxidase, cbb3-type subunit I; PFAM: Cytochrome C oxidase, monohaem subunit/FixO; Cytochrome c oxidase, subunit I; SPTR: Cytochrome cbb3 oxidase subunit I/III; TIGRFAM: Cytochrome c oxidase cbb3-type, subunit I; Cytochrome C oxidase, monohaem subunit/FixO; Belongs to [...]
  
  
 0.821
rlmN
23S rRNA m(2)A-2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family.
 
   
 0.742
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
  
 0.723
miaB
tRNA-i(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
 
   
 0.670
ruvC
Holliday junction endonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
       0.664
EHQ03248.1
Cyclase family protein; PFAM: Putative cyclase; InterPro IPR007325; KEGG: zpr:ZPR_4295 N-formylkynurenine (aryl-) formamidase; PFAM: Putative cyclase; SPTR: N-formylkynurenine (Aryl-) formamidase.
       0.627
Your Current Organism:
Gillisia limnaea
NCBI taxonomy Id: 865937
Other names: G. limnaea DSM 15749, Gillisia limnaea DSM 15749, Gillisia limnaea R-8282, Gillisia limnaea str. DSM 15749, Gillisia limnaea strain DSM 15749
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