STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHQ03305.1PFAM: Malic enzyme, NAD binding domain; Phosphate acetyl/butaryl transferase; Malic enzyme, N-terminal domain; TIGRFAM: phosphate acetyltransferase; COGs: COG0281 Malic enzyme; InterPro IPR012301:IPR012302:IPR002505; KEGG: gfo:GFO_0179 malic enzyme; PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; Phosphate acetyl/butaryl transferase; SPTR: NADP-dependent malic enzyme. (763 aa)    
Predicted Functional Partners:
EHQ01223.1
PFAM: Dehydrogenase E1 component; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain; COGs: COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit; InterPro IPR001017:IPR005475:IPR005476; KEGG: cat:CA2559_10943 putative oxidoreductase; PFAM: Dehydrogenase, E1 component; Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal; SPTR: Putative oxidoreductase.
  
 
 0.984
EHQ01456.1
Transketolase domain-containing protein; PFAM: Dehydrogenase E1 component; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain; COGs: COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit; InterPro IPR001017:IPR005475:IPR005476; KEGG: cat:CA2559_10513 (pyruvate) oxoisovalerate dehydrogenase alpha and beta fusion; PFAM: Transketolase, C-terminal; Transketolase-like, pyrimidine-binding domain; Dehydrogenase, E1 component; SPTR: (Pyruvate) Oxoisovalerate Dehydrogenase Alpha and Beta Fusion.
  
 
 0.984
fumC
Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 
 0.955
EHQ02640.1
PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; COGs: COG0469 Pyruvate kinase; InterPro IPR001697:IPR015793:IPR015794; KEGG: zpr:ZPR_0282 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, alpha/beta; SPTR: Pyruvate kinase; TIGRFAM: Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.954
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 0.947
EHQ03236.1
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
  
 
 0.946
EHQ01235.1
PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR006094:IPR004113; KEGG: zpr:ZPR_2734 FAD-linked oxidase-like protein; PFAM: FAD linked oxidase, N-terminal; FAD-linked oxidase, C-terminal; SPTR: FAD-linked oxidase-like protein.
  
 
 0.944
EHQ01898.1
Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 
 0.942
EHQ03286.1
Quinol:cytochrome c oxidoreductase iron-sulfur protein precursor; COGs: COG0437 Fe-S-cluster-containing hydrogenase components 1; InterPro IPR001450:IPR006311; KEGG: gfo:GFO_0161 iron-sulfur binding oxidoreductase; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: Iron-sulfur binding oxidoreductase.
    
 0.937
EHQ03445.1
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
   
 0.933
Your Current Organism:
Gillisia limnaea
NCBI taxonomy Id: 865937
Other names: G. limnaea DSM 15749, Gillisia limnaea DSM 15749, Gillisia limnaea R-8282, Gillisia limnaea str. DSM 15749, Gillisia limnaea strain DSM 15749
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