STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHQ03533.1NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (263 aa)    
Predicted Functional Partners:
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
 
 0.940
nadK
Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
    
 0.884
cobB
PFAM: Sir2 family; COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; HAMAP: NAD-dependent deacetylase; InterPro IPR003000; KEGG: gfo:GFO_1094 NAD-dependent deacetylase; PFAM: NAD-dependent histone deacetylase, silent information regulator Sir2; SPTR: NAD-dependent deacetylase; Belongs to the sirtuin family. Class III subfamily.
    
 0.874
EHQ02469.1
NadR-like transcriptional regulator; TIGRFAM: nicotinamide-nucleotide adenylyltransferase, NadR type; COGs: COG3172 ATPase/kinase involved in NAD metabolism; KEGG: gfo:GFO_3058 NadR-like transcriptional regulator; SPTR: NadR-like transcriptional regulator.
     
 0.856
EHQ02877.1
Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
  
 
 0.670
EHQ01625.1
Competence/damage-inducible protein CinA; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-terminal domain; competence/damage-inducible protein CinA C-terminal domain; molybdenum cofactor synthesis domain; COGs: COG1058 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; InterPro IPR001453:IPR008136:IPR008135; KEGG: fbc:FB2170_15946 putative competence-damage inducible; PFAM: CinA, C-terminal; Molybdopterin binding; SPTR: CinA-like protein; TIGRFAM: Competence-induced protein CinA; Ci [...]
    
 0.668
EHQ03534.1
TIGRFAM: gliding motility-associated lipoprotein GldB; InterPro IPR019853; KEGG: gfo:GFO_2782 gliding motility protein GldB; SPTR: Gliding motility protein GldB; TIGRFAM: Gliding motility-associated lipoprotein, GldB.
       0.643
EHQ03535.1
TIGRFAM: gliding motility-associated protein GldC; InterPro IPR019854; KEGG: zpr:ZPR_3821 gliding motility protein GldC; SPTR: Gliding motility protein GldC; TIGRFAM: Gliding motility-associated protein, GldC.
       0.643
coaD
Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
  
 
 0.554
EHQ01358.1
PFAM: NUDIX domain; COGs: COG4111 conserved hypothetical protein; InterPro IPR000086; KEGG: zpr:ZPR_2832 NUDIX family hydrolase; PFAM: NUDIX hydrolase domain; SPTR: NUDIX family hydrolase.
  
 
 0.534
Your Current Organism:
Gillisia limnaea
NCBI taxonomy Id: 865937
Other names: G. limnaea DSM 15749, Gillisia limnaea DSM 15749, Gillisia limnaea R-8282, Gillisia limnaea str. DSM 15749, Gillisia limnaea strain DSM 15749
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