node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EHQ01358.1 | EHQ01625.1 | Gilli_0647 | Gilli_0939 | PFAM: NUDIX domain; COGs: COG4111 conserved hypothetical protein; InterPro IPR000086; KEGG: zpr:ZPR_2832 NUDIX family hydrolase; PFAM: NUDIX hydrolase domain; SPTR: NUDIX family hydrolase. | Competence/damage-inducible protein CinA; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-terminal domain; competence/damage-inducible protein CinA C-terminal domain; molybdenum cofactor synthesis domain; COGs: COG1058 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; InterPro IPR001453:IPR008136:IPR008135; KEGG: fbc:FB2170_15946 putative competence-damage inducible; PFAM: CinA, C-terminal; Molybdopterin binding; SPTR: CinA-like protein; TIGRFAM: Competence-induced protein CinA; Ci [...] | 0.753 |
EHQ01358.1 | EHQ02469.1 | Gilli_0647 | Gilli_1827 | PFAM: NUDIX domain; COGs: COG4111 conserved hypothetical protein; InterPro IPR000086; KEGG: zpr:ZPR_2832 NUDIX family hydrolase; PFAM: NUDIX hydrolase domain; SPTR: NUDIX family hydrolase. | NadR-like transcriptional regulator; TIGRFAM: nicotinamide-nucleotide adenylyltransferase, NadR type; COGs: COG3172 ATPase/kinase involved in NAD metabolism; KEGG: gfo:GFO_3058 NadR-like transcriptional regulator; SPTR: NadR-like transcriptional regulator. | 0.401 |
EHQ01358.1 | EHQ02877.1 | Gilli_0647 | Gilli_2245 | PFAM: NUDIX domain; COGs: COG4111 conserved hypothetical protein; InterPro IPR000086; KEGG: zpr:ZPR_2832 NUDIX family hydrolase; PFAM: NUDIX hydrolase domain; SPTR: NUDIX family hydrolase. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.509 |
EHQ01358.1 | EHQ03533.1 | Gilli_0647 | Gilli_2922 | PFAM: NUDIX domain; COGs: COG4111 conserved hypothetical protein; InterPro IPR000086; KEGG: zpr:ZPR_2832 NUDIX family hydrolase; PFAM: NUDIX hydrolase domain; SPTR: NUDIX family hydrolase. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.534 |
EHQ01358.1 | nadD | Gilli_0647 | Gilli_2191 | PFAM: NUDIX domain; COGs: COG4111 conserved hypothetical protein; InterPro IPR000086; KEGG: zpr:ZPR_2832 NUDIX family hydrolase; PFAM: NUDIX hydrolase domain; SPTR: NUDIX family hydrolase. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.518 |
EHQ01358.1 | nadK | Gilli_0647 | Gilli_2726 | PFAM: NUDIX domain; COGs: COG4111 conserved hypothetical protein; InterPro IPR000086; KEGG: zpr:ZPR_2832 NUDIX family hydrolase; PFAM: NUDIX hydrolase domain; SPTR: NUDIX family hydrolase. | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.452 |
EHQ01625.1 | EHQ01358.1 | Gilli_0939 | Gilli_0647 | Competence/damage-inducible protein CinA; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-terminal domain; competence/damage-inducible protein CinA C-terminal domain; molybdenum cofactor synthesis domain; COGs: COG1058 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; InterPro IPR001453:IPR008136:IPR008135; KEGG: fbc:FB2170_15946 putative competence-damage inducible; PFAM: CinA, C-terminal; Molybdopterin binding; SPTR: CinA-like protein; TIGRFAM: Competence-induced protein CinA; Ci [...] | PFAM: NUDIX domain; COGs: COG4111 conserved hypothetical protein; InterPro IPR000086; KEGG: zpr:ZPR_2832 NUDIX family hydrolase; PFAM: NUDIX hydrolase domain; SPTR: NUDIX family hydrolase. | 0.753 |
EHQ01625.1 | EHQ02469.1 | Gilli_0939 | Gilli_1827 | Competence/damage-inducible protein CinA; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-terminal domain; competence/damage-inducible protein CinA C-terminal domain; molybdenum cofactor synthesis domain; COGs: COG1058 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; InterPro IPR001453:IPR008136:IPR008135; KEGG: fbc:FB2170_15946 putative competence-damage inducible; PFAM: CinA, C-terminal; Molybdopterin binding; SPTR: CinA-like protein; TIGRFAM: Competence-induced protein CinA; Ci [...] | NadR-like transcriptional regulator; TIGRFAM: nicotinamide-nucleotide adenylyltransferase, NadR type; COGs: COG3172 ATPase/kinase involved in NAD metabolism; KEGG: gfo:GFO_3058 NadR-like transcriptional regulator; SPTR: NadR-like transcriptional regulator. | 0.855 |
EHQ01625.1 | EHQ02877.1 | Gilli_0939 | Gilli_2245 | Competence/damage-inducible protein CinA; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-terminal domain; competence/damage-inducible protein CinA C-terminal domain; molybdenum cofactor synthesis domain; COGs: COG1058 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; InterPro IPR001453:IPR008136:IPR008135; KEGG: fbc:FB2170_15946 putative competence-damage inducible; PFAM: CinA, C-terminal; Molybdopterin binding; SPTR: CinA-like protein; TIGRFAM: Competence-induced protein CinA; Ci [...] | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.918 |
EHQ01625.1 | EHQ03533.1 | Gilli_0939 | Gilli_2922 | Competence/damage-inducible protein CinA; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-terminal domain; competence/damage-inducible protein CinA C-terminal domain; molybdenum cofactor synthesis domain; COGs: COG1058 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; InterPro IPR001453:IPR008136:IPR008135; KEGG: fbc:FB2170_15946 putative competence-damage inducible; PFAM: CinA, C-terminal; Molybdopterin binding; SPTR: CinA-like protein; TIGRFAM: Competence-induced protein CinA; Ci [...] | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.668 |
EHQ01625.1 | coaD | Gilli_0939 | Gilli_2827 | Competence/damage-inducible protein CinA; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-terminal domain; competence/damage-inducible protein CinA C-terminal domain; molybdenum cofactor synthesis domain; COGs: COG1058 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; InterPro IPR001453:IPR008136:IPR008135; KEGG: fbc:FB2170_15946 putative competence-damage inducible; PFAM: CinA, C-terminal; Molybdopterin binding; SPTR: CinA-like protein; TIGRFAM: Competence-induced protein CinA; Ci [...] | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.450 |
EHQ01625.1 | cobB | Gilli_0939 | Gilli_3538 | Competence/damage-inducible protein CinA; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-terminal domain; competence/damage-inducible protein CinA C-terminal domain; molybdenum cofactor synthesis domain; COGs: COG1058 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; InterPro IPR001453:IPR008136:IPR008135; KEGG: fbc:FB2170_15946 putative competence-damage inducible; PFAM: CinA, C-terminal; Molybdopterin binding; SPTR: CinA-like protein; TIGRFAM: Competence-induced protein CinA; Ci [...] | PFAM: Sir2 family; COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; HAMAP: NAD-dependent deacetylase; InterPro IPR003000; KEGG: gfo:GFO_1094 NAD-dependent deacetylase; PFAM: NAD-dependent histone deacetylase, silent information regulator Sir2; SPTR: NAD-dependent deacetylase; Belongs to the sirtuin family. Class III subfamily. | 0.596 |
EHQ01625.1 | nadD | Gilli_0939 | Gilli_2191 | Competence/damage-inducible protein CinA; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-terminal domain; competence/damage-inducible protein CinA C-terminal domain; molybdenum cofactor synthesis domain; COGs: COG1058 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; InterPro IPR001453:IPR008136:IPR008135; KEGG: fbc:FB2170_15946 putative competence-damage inducible; PFAM: CinA, C-terminal; Molybdopterin binding; SPTR: CinA-like protein; TIGRFAM: Competence-induced protein CinA; Ci [...] | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.920 |
EHQ01625.1 | nadK | Gilli_0939 | Gilli_2726 | Competence/damage-inducible protein CinA; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-terminal domain; competence/damage-inducible protein CinA C-terminal domain; molybdenum cofactor synthesis domain; COGs: COG1058 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; InterPro IPR001453:IPR008136:IPR008135; KEGG: fbc:FB2170_15946 putative competence-damage inducible; PFAM: CinA, C-terminal; Molybdopterin binding; SPTR: CinA-like protein; TIGRFAM: Competence-induced protein CinA; Ci [...] | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.521 |
EHQ02469.1 | EHQ01358.1 | Gilli_1827 | Gilli_0647 | NadR-like transcriptional regulator; TIGRFAM: nicotinamide-nucleotide adenylyltransferase, NadR type; COGs: COG3172 ATPase/kinase involved in NAD metabolism; KEGG: gfo:GFO_3058 NadR-like transcriptional regulator; SPTR: NadR-like transcriptional regulator. | PFAM: NUDIX domain; COGs: COG4111 conserved hypothetical protein; InterPro IPR000086; KEGG: zpr:ZPR_2832 NUDIX family hydrolase; PFAM: NUDIX hydrolase domain; SPTR: NUDIX family hydrolase. | 0.401 |
EHQ02469.1 | EHQ01625.1 | Gilli_1827 | Gilli_0939 | NadR-like transcriptional regulator; TIGRFAM: nicotinamide-nucleotide adenylyltransferase, NadR type; COGs: COG3172 ATPase/kinase involved in NAD metabolism; KEGG: gfo:GFO_3058 NadR-like transcriptional regulator; SPTR: NadR-like transcriptional regulator. | Competence/damage-inducible protein CinA; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-terminal domain; competence/damage-inducible protein CinA C-terminal domain; molybdenum cofactor synthesis domain; COGs: COG1058 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; InterPro IPR001453:IPR008136:IPR008135; KEGG: fbc:FB2170_15946 putative competence-damage inducible; PFAM: CinA, C-terminal; Molybdopterin binding; SPTR: CinA-like protein; TIGRFAM: Competence-induced protein CinA; Ci [...] | 0.855 |
EHQ02469.1 | EHQ02877.1 | Gilli_1827 | Gilli_2245 | NadR-like transcriptional regulator; TIGRFAM: nicotinamide-nucleotide adenylyltransferase, NadR type; COGs: COG3172 ATPase/kinase involved in NAD metabolism; KEGG: gfo:GFO_3058 NadR-like transcriptional regulator; SPTR: NadR-like transcriptional regulator. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.462 |
EHQ02469.1 | EHQ03533.1 | Gilli_1827 | Gilli_2922 | NadR-like transcriptional regulator; TIGRFAM: nicotinamide-nucleotide adenylyltransferase, NadR type; COGs: COG3172 ATPase/kinase involved in NAD metabolism; KEGG: gfo:GFO_3058 NadR-like transcriptional regulator; SPTR: NadR-like transcriptional regulator. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.856 |
EHQ02469.1 | cobB | Gilli_1827 | Gilli_3538 | NadR-like transcriptional regulator; TIGRFAM: nicotinamide-nucleotide adenylyltransferase, NadR type; COGs: COG3172 ATPase/kinase involved in NAD metabolism; KEGG: gfo:GFO_3058 NadR-like transcriptional regulator; SPTR: NadR-like transcriptional regulator. | PFAM: Sir2 family; COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; HAMAP: NAD-dependent deacetylase; InterPro IPR003000; KEGG: gfo:GFO_1094 NAD-dependent deacetylase; PFAM: NAD-dependent histone deacetylase, silent information regulator Sir2; SPTR: NAD-dependent deacetylase; Belongs to the sirtuin family. Class III subfamily. | 0.930 |
EHQ02469.1 | nadD | Gilli_1827 | Gilli_2191 | NadR-like transcriptional regulator; TIGRFAM: nicotinamide-nucleotide adenylyltransferase, NadR type; COGs: COG3172 ATPase/kinase involved in NAD metabolism; KEGG: gfo:GFO_3058 NadR-like transcriptional regulator; SPTR: NadR-like transcriptional regulator. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.857 |