STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADX67156.1Hypothetical protein; KEGG: amc:MADE_03446 putative orphan protein; SPTR: Putative orphan protein; PFAM: Peptidase family M49. (552 aa)    
Predicted Functional Partners:
ADX67063.1
Heat shock protein Hsp90; COGs: COG0326 Molecular chaperone HSP90 family; InterPro IPR003594:IPR020576; KEGG: fba:FIC_00241 heat shock protein 90; PFAM: Heat shock protein Hsp90, C-terminal; ATPase-like, ATP-binding domain; SPTR: Chaperone HtpG; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Hsp90 protein.
   
 0.813
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
 0.801
dnaK
Chaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.797
ADX68765.1
Cholesterol oxidase; COGs: COG2303 Choline dehydrogenase and related flavoprotein; InterPro IPR006076; KEGG: sen:SACE_6417 cholesterol oxidase; PFAM: FAD dependent oxidoreductase; PRIAM: Cholesterol oxidase; SPTR: Cholesterol oxidase; PFAM: GMC oxidoreductase.
  
 
 0.765
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.727
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.686
ADX67020.1
Ankyrin; COGs: COG0666 FOG: Ankyrin repeat; InterPro IPR002110; KEGG: dfe:Dfer_4030 ankyrin; SMART: Ankyrin repeat; SPTR: Ankyrin repeat domain protein; PFAM: Ankyrin repeat.
   
 0.676
ADX67043.1
Ankyrin repeat protein; InterPro IPR002110; KEGG: dfe:Dfer_1667 ankyrin; SPTR: Ankyrin; PFAM: Ankyrin repeat.
   
 0.676
dnaJ
Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
    
 0.662
ADX68743.1
Heat shock protein DnaJ domain protein; COGs: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; InterPro IPR001623:IPR002939; KEGG: bfs:BF3207 putative chaperone; PFAM: Heat shock protein DnaJ, N-terminal; Chaperone DnaJ, C-terminal; SMART: Heat shock protein DnaJ, N-terminal; SPTR: Putative chaperone; PFAM: DnaJ domain; DnaJ C terminal region.
    
 0.662
Your Current Organism:
Weeksella virosa
NCBI taxonomy Id: 865938
Other names: W. virosa DSM 16922, Weeksella virosa ATCC 43766, Weeksella virosa CIP 103040, Weeksella virosa DSM 16922, Weeksella virosa str. DSM 16922, Weeksella virosa strain DSM 16922
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