STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpFCOGs: COG0135 Phosphoribosylanthranilate isomerase; InterPro IPR001240; KEGG: pdi:BDI_0587 N-(5'-phosphoribosyl) anthranilate isomerase; PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); PRIAM: Phosphoribosylanthranilate isomerase; SPTR: N-(5'-phosphoribosyl)anthranilate isomerase; PFAM: N-(5'phosphoribosyl)anthranilate (PRA) isomerase; Belongs to the TrpF family. (211 aa)    
Predicted Functional Partners:
ADX67641.1
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 
 0.999
ADX67642.1
COGs: COG0134 Indole-3-glycerol phosphate synthase; InterPro IPR013798; KEGG: cpi:Cpin_1825 indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; PRIAM: Indole-3-glycerol-phosphate synthase; SPTR: Indole-3-glycerol phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; Belongs to the TrpC family.
 
 0.999
trpB
Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
 0.999
ADX67640.1
Glutamine amidotransferase of anthranilate synthase; COGs: COG0512 Anthranilate/para-aminobenzoate synthase component II; InterPro IPR006221:IPR000991; KEGG: smh:DMIN_01210 anthranilate synthase, component II; PFAM: Glutamine amidotransferase class-I, C-terminal; PRIAM: Anthranilate synthase; SPTR: Putative uncharacterized protein; TIGRFAM: Anthranilate synthase, glutamine amidotransferase domain; PFAM: Glutamine amidotransferase class-I; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase.
  
 0.994
trpA
Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
  
 0.994
ADX67639.1
COGs: COG0147 Anthranilate/para-aminobenzoate synthase component I; InterPro IPR006805:IPR015890; KEGG: zpr:ZPR_0835 anthranilate synthase component I; PFAM: Chorismate binding, C-terminal; Anthranilate synthase component I, N-terminal; PRIAM: Anthranilate synthase; SPTR: Anthranilate synthase component I; PFAM: Anthranilate synthase component I, N terminal region; chorismate binding enzyme.
 
  
 0.985
ADX67838.1
COGs: COG0147 Anthranilate/para-aminobenzoate synthase component I; InterPro IPR015890; KEGG: dfe:Dfer_3375 para-aminobenzoate synthase component I; PFAM: Chorismate binding, C-terminal; PRIAM: Aminodeoxychorismate synthase; SPTR: Chorismate binding-like protein; PFAM: chorismate binding enzyme.
 
  
 0.824
ADX67104.1
Chorismate binding domain-containing protein; COGs: COG1169 Isochorismate synthase; InterPro IPR015890; KEGG: bpi:BPLAN_443 isochorismate synthase EntC; PFAM: Chorismate binding, C-terminal; SPTR: Isochorismate synthase entC; PFAM: chorismate binding enzyme; TIGRFAM: isochorismate synthases.
  
   
 0.590
ADX68021.1
COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR002701:IPR006218:IPR020822; KEGG: fba:FIC_01361 2-keto-3-deoxy-D-arabino-heptulosonate-7-phosphate synthase I beta; PFAM: DAHP synthetase I/KDSA; Chorismate mutase, type II; PRIAM: 3-deoxy-7-phosphoheptulonate synthase; SMART: Chorismate mutase; SPTR:2-keto-3-deoxy-D-arabino-heptulosonate-7- phosphate synthase I beta; PFAM: Chorismate mutase type II; DAHP synthetase I family; TIGRFAM: chorismate mutase related enzymes; phospho-2-dehydro-3-deoxyheptonate aldolase.
  
  
 0.583
pyrE
Orotidine 5'-phosphate decarboxylase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
  
 0.533
Your Current Organism:
Weeksella virosa
NCBI taxonomy Id: 865938
Other names: W. virosa DSM 16922, Weeksella virosa ATCC 43766, Weeksella virosa CIP 103040, Weeksella virosa DSM 16922, Weeksella virosa str. DSM 16922, Weeksella virosa strain DSM 16922
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