STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADX68053.1InterPro IPR019734:IPR001440; KEGG: fba:FIC_01062 TPR repeat protein; PFAM: Tetratricopeptide TPR-1; SMART: Tetratricopeptide repeat; SPTR: Tetratricopeptide repeat family protein; PFAM: Tetratricopeptide repeat. (394 aa)    
Predicted Functional Partners:
gyrA
DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
       0.803
ADX68419.1
Protein of unknown function DUF490; COGs: COG2911 conserved hypothetical protein; InterPro IPR007452; KEGG: fba:FIC_00499 hypothetical protein; PFAM: Protein of unknown function DUF490; SPTR: Putative uncharacterized protein; PFAM: Family of unknown function (DUF490).
  
     0.769
ADX67124.1
KEGG: aas:Aasi_0268 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Bacterial transcription activator, effector binding domain.
  
     0.750
ADX67857.1
KEGG: fba:FIC_00222 hypothetical protein; SPTR: Putative uncharacterized protein.
 
    0.745
ADX67127.1
KEGG: fba:FIC_02507 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.742
ADX67903.1
KEGG: fba:FIC_02312 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.740
ADX67317.1
KEGG: fba:FIC_00189 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.723
ADX67382.1
Surface antigen (D15); COGs: COG4775 Outer membrane protein/protective antigen OMA87; InterPro IPR000184; KEGG: fba:FIC_01279 hypothetical protein; PFAM: Bacterial surface antigen (D15); SPTR: Putative uncharacterized protein; PFAM: Surface antigen variable number repeat; Surface antigen.
  
     0.721
ADX67689.1
KEGG: fba:FIC_00486 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.719
ADX67424.1
InterPro IPR005017; KEGG: fba:FIC_01638 putative hemin receptor; PFAM: Membrane protein, aromatic hydrocarbon degradation; SPTR: Hemin receptor.
  
     0.717
Your Current Organism:
Weeksella virosa
NCBI taxonomy Id: 865938
Other names: W. virosa DSM 16922, Weeksella virosa ATCC 43766, Weeksella virosa CIP 103040, Weeksella virosa DSM 16922, Weeksella virosa str. DSM 16922, Weeksella virosa strain DSM 16922
Server load: low (16%) [HD]