node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADX66926.1 | ADX67021.1 | Weevi_0204 | Weevi_0299 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR011607:IPR006275:IPR005481:IPR005479:IPR 005480; KEGG: bth:BT_0557 carbamyl phosphate synthetase; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Carbamoyl-phosphate synthetase, large subunit, oligomerisation; Methylglyoxal synthase-like domain; PRIAM: Carbamoyl-phosphate synthase (ammonia); SMART: Methylglyoxal synthase-like domain; SPTR: Putative uncharacterized protein; TIGRFAM: Carbamoyl-phosphate synthase, large subunit; [...] | 0.587 |
ADX66926.1 | guaA | Weevi_0204 | Weevi_1663 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.649 |
ADX66926.1 | pdxH | Weevi_0204 | Weevi_1647 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Pyridoxine/pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.454 |
ADX66926.1 | pdxJ | Weevi_0204 | Weevi_1297 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Pyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.528 |
ADX66926.1 | ribB | Weevi_0204 | Weevi_0761 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.999 |
ADX67021.1 | ADX66926.1 | Weevi_0299 | Weevi_0204 | COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR011607:IPR006275:IPR005481:IPR005479:IPR 005480; KEGG: bth:BT_0557 carbamyl phosphate synthetase; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Carbamoyl-phosphate synthetase, large subunit, oligomerisation; Methylglyoxal synthase-like domain; PRIAM: Carbamoyl-phosphate synthase (ammonia); SMART: Methylglyoxal synthase-like domain; SPTR: Putative uncharacterized protein; TIGRFAM: Carbamoyl-phosphate synthase, large subunit; [...] | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.587 |
ADX67021.1 | guaA | Weevi_0299 | Weevi_1663 | COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR011607:IPR006275:IPR005481:IPR005479:IPR 005480; KEGG: bth:BT_0557 carbamyl phosphate synthetase; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Carbamoyl-phosphate synthetase, large subunit, oligomerisation; Methylglyoxal synthase-like domain; PRIAM: Carbamoyl-phosphate synthase (ammonia); SMART: Methylglyoxal synthase-like domain; SPTR: Putative uncharacterized protein; TIGRFAM: Carbamoyl-phosphate synthase, large subunit; [...] | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.841 |
ADX67021.1 | pdxH | Weevi_0299 | Weevi_1647 | COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR011607:IPR006275:IPR005481:IPR005479:IPR 005480; KEGG: bth:BT_0557 carbamyl phosphate synthetase; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Carbamoyl-phosphate synthetase, large subunit, oligomerisation; Methylglyoxal synthase-like domain; PRIAM: Carbamoyl-phosphate synthase (ammonia); SMART: Methylglyoxal synthase-like domain; SPTR: Putative uncharacterized protein; TIGRFAM: Carbamoyl-phosphate synthase, large subunit; [...] | Pyridoxine/pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.422 |
ADX67021.1 | ribB | Weevi_0299 | Weevi_0761 | COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR011607:IPR006275:IPR005481:IPR005479:IPR 005480; KEGG: bth:BT_0557 carbamyl phosphate synthetase; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Carbamoyl-phosphate synthetase, large subunit, oligomerisation; Methylglyoxal synthase-like domain; PRIAM: Carbamoyl-phosphate synthase (ammonia); SMART: Methylglyoxal synthase-like domain; SPTR: Putative uncharacterized protein; TIGRFAM: Carbamoyl-phosphate synthase, large subunit; [...] | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.437 |
ADX68325.1 | guaA | Weevi_1627 | Weevi_1663 | COGs: COG1003 Glycine cleavage system protein P (pyridoxal-binding) C-terminal domain; InterPro IPR003437:IPR020580; KEGG: fba:FIC_00985 glycine dehydrogenase; PFAM: Glycine cleavage system P-protein, N-terminal; SPTR: Glycine dehydrogenase (Decarboxylating); TIGRFAM: Glycine cleavage system P protein, homodimeric; PFAM: Glycine cleavage system P-protein; TIGRFAM: glycine dehydrogenase (decarboxylating); Belongs to the GcvP family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.645 |
ADX68325.1 | pdxH | Weevi_1627 | Weevi_1647 | COGs: COG1003 Glycine cleavage system protein P (pyridoxal-binding) C-terminal domain; InterPro IPR003437:IPR020580; KEGG: fba:FIC_00985 glycine dehydrogenase; PFAM: Glycine cleavage system P-protein, N-terminal; SPTR: Glycine dehydrogenase (Decarboxylating); TIGRFAM: Glycine cleavage system P protein, homodimeric; PFAM: Glycine cleavage system P-protein; TIGRFAM: glycine dehydrogenase (decarboxylating); Belongs to the GcvP family. | Pyridoxine/pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.531 |
ADX68325.1 | pdxJ | Weevi_1627 | Weevi_1297 | COGs: COG1003 Glycine cleavage system protein P (pyridoxal-binding) C-terminal domain; InterPro IPR003437:IPR020580; KEGG: fba:FIC_00985 glycine dehydrogenase; PFAM: Glycine cleavage system P-protein, N-terminal; SPTR: Glycine dehydrogenase (Decarboxylating); TIGRFAM: Glycine cleavage system P protein, homodimeric; PFAM: Glycine cleavage system P-protein; TIGRFAM: glycine dehydrogenase (decarboxylating); Belongs to the GcvP family. | Pyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.430 |
ADX68343.1 | pdxH | Weevi_1646 | Weevi_1647 | Protein of unknown function DUF179; COGs: COG1678 Putative transcriptional regulator protein; InterPro IPR003774; KEGG: zpr:ZPR_2523 hypothetical protein; PFAM: Protein of unknown function DUF179; SPTR: Putative transcriptional regulator; PFAM: Uncharacterized ACR, COG1678; Belongs to the UPF0301 (AlgH) family. | Pyridoxine/pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.658 |
guaA | ADX66926.1 | Weevi_1663 | Weevi_0204 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.649 |
guaA | ADX67021.1 | Weevi_1663 | Weevi_0299 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR011607:IPR006275:IPR005481:IPR005479:IPR 005480; KEGG: bth:BT_0557 carbamyl phosphate synthetase; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Carbamoyl-phosphate synthetase, large subunit, oligomerisation; Methylglyoxal synthase-like domain; PRIAM: Carbamoyl-phosphate synthase (ammonia); SMART: Methylglyoxal synthase-like domain; SPTR: Putative uncharacterized protein; TIGRFAM: Carbamoyl-phosphate synthase, large subunit; [...] | 0.841 |
guaA | ADX68325.1 | Weevi_1663 | Weevi_1627 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | COGs: COG1003 Glycine cleavage system protein P (pyridoxal-binding) C-terminal domain; InterPro IPR003437:IPR020580; KEGG: fba:FIC_00985 glycine dehydrogenase; PFAM: Glycine cleavage system P-protein, N-terminal; SPTR: Glycine dehydrogenase (Decarboxylating); TIGRFAM: Glycine cleavage system P protein, homodimeric; PFAM: Glycine cleavage system P-protein; TIGRFAM: glycine dehydrogenase (decarboxylating); Belongs to the GcvP family. | 0.645 |
guaA | pdxH | Weevi_1663 | Weevi_1647 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Pyridoxine/pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.447 |
guaA | pdxJ | Weevi_1663 | Weevi_1297 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Pyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.492 |
guaA | ribB | Weevi_1663 | Weevi_0761 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.760 |
pdxH | ADX66926.1 | Weevi_1647 | Weevi_0204 | Pyridoxine/pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.454 |