STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
icmFMethylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. (1155 aa)    
Predicted Functional Partners:
ADX67973.1
COGs: COG1884 Methylmalonyl-CoA mutase N-terminal domain/subunit; InterPro IPR006099:IPR006158:IPR006098:IPR006159; KEGG: zpr:ZPR_1469 methylmalonyl-CoA mutase; PFAM: Methylmalonyl-CoA mutase, alpha/beta chain, catalytic; Cobalamin (vitamin B12)-binding; PRIAM: Methylmalonyl-CoA mutase; SPTR: Methylmalonyl-CoA mutase; TIGRFAM: Methylmalonyl-CoA mutase, alpha chain, catalytic; Methylmalonyl-CoA mutase, C-terminal; PFAM: Methylmalonyl-CoA mutase; B12 binding domain; TIGRFAM: methylmalonyl-CoA mutase N-terminal domain; methylmalonyl-CoA mutase C-terminal domain.
 
 
0.999
ADX67210.1
Succinate CoA transferase; COGs: COG0427 Acetyl-CoA hydrolase; InterPro IPR003702:IPR017821; KEGG: bba:Bd1620 acetyl-CoA hydrolase/transferase family protein; PFAM: Acetyl-CoA hydrolase/transferase; PRIAM: Acetyl-CoA hydrolase; SPTR: Acetyl-CoA hydrolase/transferase family protein; TIGRFAM: Succinate CoA transferase; PFAM: Acetyl-CoA hydrolase/transferase N-terminal domain; Citrate lyase, alpha subunit (CitF); TIGRFAM: succinate CoA transferases.
  
  
 0.878
ADX68501.1
COGs: COG1884 Methylmalonyl-CoA mutase N-terminal domain/subunit; InterPro IPR006099; KEGG: fbc:FB2170_09636 methylmalonyl-CoA mutase small subunit; PFAM: Methylmalonyl-CoA mutase, alpha/beta chain, catalytic; PRIAM: Methylmalonyl-CoA mutase; SPTR: Putative methylmalonyl-CoA mutase small subunit; PFAM: Methylmalonyl-CoA mutase.
 
 
0.871
ADX67569.1
LAO/AO transport system ATPase; COGs: COG1703 Putative periplasmic protein kinase ArgK and related GTPase of G3E family; InterPro IPR005129; KEGG: fba:FIC_00117 LAO/AO transport system ATPase; PFAM: ArgK protein; SPTR: LAO/AO transport system ATPase; TIGRFAM: ArgK protein; PFAM: ArgK protein; TIGRFAM: LAO/AO transport system ATPase.
 
  
0.833
ADX68703.1
COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873; KEGG: fjo:Fjoh_4782 acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II-like protein; PFAM: AMP-dependent synthetase/ligase; SPTR: O-succinylbenzoic acid--CoA ligase; PFAM: AMP-binding enzyme.
     
 0.718
ADX67119.1
COGs: COG1250 3-hydroxyacyl-CoA dehydrogenase; InterPro IPR006176:IPR006108:IPR001753; KEGG: fbc:FB2170_13963 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase/carnithine racemase fusion; PFAM: 3-hydroxyacyl-CoA dehydrogenase, NAD binding; 3-hydroxyacyl-CoA dehydrogenase, C-terminal; Crotonase, core; SPTR: 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase/carnithine racemase fusion; PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.
  
  
 0.706
ADX68387.1
Periplasmic binding protein; COGs: COG0614 ABC-type Fe3+-hydroxamate transport system periplasmic component; InterPro IPR002491; KEGG: pol:Bpro_2784 periplasmic binding protein; PFAM: Periplasmic binding protein; SPTR: Periplasmic binding protein; PFAM: Periplasmic binding protein.
 
  
 0.671
metG
Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
     
 0.628
ADX67311.1
COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR000022; KEGG: fps:FP1002 carboxyltransferase; PFAM: Carboxyl transferase; PRIAM: Methylcrotonoyl-CoA carboxylase; SPTR: Propionyl-CoA carboxylase beta subunit; PFAM: Carboxyl transferase domain.
  
  
 0.610
ADX68153.1
acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
  
 0.589
Your Current Organism:
Weeksella virosa
NCBI taxonomy Id: 865938
Other names: W. virosa DSM 16922, Weeksella virosa ATCC 43766, Weeksella virosa CIP 103040, Weeksella virosa DSM 16922, Weeksella virosa str. DSM 16922, Weeksella virosa strain DSM 16922
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