STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PFY1_1Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. (126 aa)    
Predicted Functional Partners:
ACT1_1
Actin.
    
 0.911
ACT1_2
Actin; Belongs to the actin family.
    
 0.911
ACTIN2
Actin-2; Belongs to the actin family.
    
 0.911
CU097_014610
Adenylyl cyclase-associated protein; Belongs to the CAP family.
   
 0.861
DAAM1
Disheveled-associated activator of morphoproteinsis 1.
    
 0.832
CU097_003861
GBD/FH3 domain-containing protein.
    
 0.832
DAAM2
Dishevelled associated activator of morphoproteinsis 2.
    
 0.832
DIAPH3
Diaphanous.
    
 0.832
CU097_012505
FH2 domain-containing protein.
    
 0.832
CU097_014369
GBD/FH3 domain-containing protein.
    
 0.832
Your Current Organism:
Rhizopus azygosporus
NCBI taxonomy Id: 86630
Other names: ATCC 48108, CBS 357.93, R. azygosporus, Rhizopus microsporus var. azygosporus
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