STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AP4E1_2AP-4 complex subunit epsilon-1. (400 aa)    
Predicted Functional Partners:
AP1M1_2
AP-1 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.
   
 0.984
AP2B1
AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
   
 0.959
APL2
AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
   
 0.959
AP3S1
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
    
 0.955
VAS2_1
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
    
 0.951
VAS2_2
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
    
 0.951
AP3M2
AP-3 complex subunit mu-2; Belongs to the adaptor complexes medium subunit family.
   
 0.947
CU097_005644
MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.
   
 0.932
CU097_014615
MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.
   
 0.932
APS2_2
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
   
 0.926
Your Current Organism:
Rhizopus azygosporus
NCBI taxonomy Id: 86630
Other names: ATCC 48108, CBS 357.93, R. azygosporus, Rhizopus microsporus var. azygosporus
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