STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HIS3_1Imidazoleglycerol-phosphate dehydratase; Belongs to the imidazoleglycerol-phosphate dehydratase family. (197 aa)    
Predicted Functional Partners:
HIS4_2
Trifunctional histidinol dehydrogenase.
 
 0.996
HIS5
Histidinol-phosphate transaminase.
 
 0.996
HIS4_1
Trifunctional histidinol dehydrogenase.
 
 
 0.995
HIS7_1
Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.
 
 
 0.982
HIS7_2
Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.
 
 
 0.982
HIS6_1
Enzyme that catalyzes the fourth step in the histidine pathway; Belongs to the HisA/HisF family.
  
 
 0.976
HIS6_2
Enzyme that catalyzes the fourth step in the histidine pathway; Belongs to the HisA/HisF family.
  
 
 0.976
HIS1
ATP phosphoribosyltransferase (ATP-PRTase) (ATP-PRT).
 
  
 0.974
CU097_013852
Aminotran_1_2 domain-containing protein.
  
 
 0.958
RAD16
DNA repair protein rad16.
  
 
 0.958
Your Current Organism:
Rhizopus azygosporus
NCBI taxonomy Id: 86630
Other names: ATCC 48108, CBS 357.93, R. azygosporus, Rhizopus microsporus var. azygosporus
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