Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
trxBThioredoxin-disulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (316 aa)    
Predicted Functional Partners:
trxA
Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thioredoxin family.
 
 0.985
AQX53312.1
Cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
  
 
  0.917
AQX55618.1
Pyridine nucleotide-disulfide oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.917
megL
Thioredoxin reductase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.901
AQX53267.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.802
AQX53269.1
NUDIX hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.730
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
     
 0.697
ahpC
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
  
 
 0.627
AQX55367.1
Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.627
tpx
Lipid hydroperoxide peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily.
  
  
 0.626
Your Current Organism:
Bacillus flexus
NCBI taxonomy Id: 86664
Other names: ATCC 49095, B. flexus, Bacillus sp. Fu, Bacillus sp. OS46R, Bacillus sp. PRD 213, CCUG 28525, CIP 106928, HAMBI 2080, IFO 15715, JCM 12301, LMG 11155, LMG:11155, NBRC 15715, NRRL NRS-665
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