Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AQX53386.1Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology. (128 aa)    
Predicted Functional Partners:
AQX54731.1
Glyoxal reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  0.915
AQX55685.1
Glyoxal reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  0.915
AQX54658.1
Zn-dependent hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.911
AQX53756.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  0.906
aldA
Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family.
   
  0.906
trpB
Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
   
  0.817
ilvA
Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
   
 
  0.802
trpA
Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
     
  0.800
sdaAB
Transcriptional regulator; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
  0.800
sdaAA
L-serine dehydratase, iron-sulfur-dependent subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
  0.800
Your Current Organism:
Bacillus flexus
NCBI taxonomy Id: 86664
Other names: ATCC 49095, B. flexus, Bacillus sp. Fu, Bacillus sp. OS46R, Bacillus sp. PRD 213, CCUG 28525, CIP 106928, HAMBI 2080, IFO 15715, JCM 12301, LMG 11155, LMG:11155, NBRC 15715, NRRL NRS-665
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.