Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AQX53538.1dUTPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (162 aa)    
Predicted Functional Partners:
AQX56394.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.760
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
    
 0.669
AQX53539.1
Peptidase M28; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.636
AQX54218.1
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
   
  
 0.602
AQX54190.1
Resolvase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.542
AQX53453.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.533
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
     
  0.500
AQX55042.1
acyl-CoA--6-aminopenicillanic acid acyl-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.450
AQX55504.1
ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.438
AQX54058.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.417
Your Current Organism:
Bacillus flexus
NCBI taxonomy Id: 86664
Other names: ATCC 49095, B. flexus, Bacillus sp. Fu, Bacillus sp. OS46R, Bacillus sp. PRD 213, CCUG 28525, CIP 106928, HAMBI 2080, IFO 15715, JCM 12301, LMG 11155, LMG:11155, NBRC 15715, NRRL NRS-665
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