Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fosBFosfomycin resistance protein FosB; Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor. Belongs to the fosfomycin resistance protein family. FosB subfamily. (144 aa)    
Predicted Functional Partners:
AQX54349.1
Erythromycin esterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.745
AQX54831.1
ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AAA ATPase family.
  
    0.530
AQX54242.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
     0.528
bshC
Bacillithiol biosynthesis cysteine-adding enzyme BshC; Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH.
      
 0.522
AQX54351.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.493
AQX55304.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.492
AQX54352.1
Dipeptide epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.463
birA
3-methyl-2-oxobutanoate hydroxymethyltransferase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
    0.450
AQX54614.1
NAD-dependent dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.446
AQX53204.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.444
Your Current Organism:
Bacillus flexus
NCBI taxonomy Id: 86664
Other names: ATCC 49095, B. flexus, Bacillus sp. Fu, Bacillus sp. OS46R, Bacillus sp. PRD 213, CCUG 28525, CIP 106928, HAMBI 2080, IFO 15715, JCM 12301, LMG 11155, LMG:11155, NBRC 15715, NRRL NRS-665
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