hup-4 protein (Prevotella disiens) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

hup-4

DNA-binding protein HU; Identified by match to protein family HMM PF00216; overlaps another CDS with the same product name; Belongs to the bacterial histone-like protein family. (408 aa)

Predicted Functional Partners:

EFL45041.1

0.907

hup-3

0.823

guaA

0.821

EFL45635.1

0.771

EFL45692.1

0.770

EFL46866.1

0.764

guaB

0.759

EFL46407.1

0.757

EFL45398.1

0.755

EFL45226.1

0.747

Your Current Organism:

Prevotella disiens

NCBI taxonomy Id: 866771
Other names: P. disiens FB035-09AN, Prevotella disiens FB035-09AN

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EFL45041.1	hup-4	HMPREF9296_0862	HMPREF9296_2001	Putative lysozyme; Identified by match to protein family HMM PF04965.	DNA-binding protein HU; Identified by match to protein family HMM PF00216; overlaps another CDS with the same product name; Belongs to the bacterial histone-like protein family.	0.907
EFL45226.1	EFL45398.1	HMPREF9296_1900	HMPREF9296_0476	Hypothetical protein.	Hypothetical protein.	0.770
EFL45226.1	EFL45635.1	HMPREF9296_1900	HMPREF9296_1568	Hypothetical protein.	Hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop.	0.733
EFL45226.1	EFL45692.1	HMPREF9296_1900	HMPREF9296_1653	Hypothetical protein.	Hypothetical protein.	0.749
EFL45226.1	EFL46407.1	HMPREF9296_1900	HMPREF9296_0932	Hypothetical protein.	Hypothetical protein.	0.766
EFL45226.1	EFL46866.1	HMPREF9296_1900	HMPREF9296_2648	Hypothetical protein.	Hypothetical protein.	0.761
EFL45226.1	hup-4	HMPREF9296_1900	HMPREF9296_2001	Hypothetical protein.	DNA-binding protein HU; Identified by match to protein family HMM PF00216; overlaps another CDS with the same product name; Belongs to the bacterial histone-like protein family.	0.747
EFL45398.1	EFL45226.1	HMPREF9296_0476	HMPREF9296_1900	Hypothetical protein.	Hypothetical protein.	0.770
EFL45398.1	EFL45635.1	HMPREF9296_0476	HMPREF9296_1568	Hypothetical protein.	Hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop.	0.752
EFL45398.1	EFL45692.1	HMPREF9296_0476	HMPREF9296_1653	Hypothetical protein.	Hypothetical protein.	0.764
EFL45398.1	EFL46407.1	HMPREF9296_0476	HMPREF9296_0932	Hypothetical protein.	Hypothetical protein.	0.774
EFL45398.1	EFL46866.1	HMPREF9296_0476	HMPREF9296_2648	Hypothetical protein.	Hypothetical protein.	0.770
EFL45398.1	hup-4	HMPREF9296_0476	HMPREF9296_2001	Hypothetical protein.	DNA-binding protein HU; Identified by match to protein family HMM PF00216; overlaps another CDS with the same product name; Belongs to the bacterial histone-like protein family.	0.755
EFL45635.1	EFL45226.1	HMPREF9296_1568	HMPREF9296_1900	Hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop.	Hypothetical protein.	0.733
EFL45635.1	EFL45398.1	HMPREF9296_1568	HMPREF9296_0476	Hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop.	Hypothetical protein.	0.752
EFL45635.1	EFL45692.1	HMPREF9296_1568	HMPREF9296_1653	Hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop.	Hypothetical protein.	0.728
EFL45635.1	EFL46407.1	HMPREF9296_1568	HMPREF9296_0932	Hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop.	Hypothetical protein.	0.890
EFL45635.1	EFL46866.1	HMPREF9296_1568	HMPREF9296_2648	Hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop.	Hypothetical protein.	0.726
EFL45635.1	guaA	HMPREF9296_1568	HMPREF9296_2598	Hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop.	GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP.	0.566
EFL45635.1	guaB	HMPREF9296_1568	HMPREF9296_2352	Hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.512

page 1 of 3

Server load: low (32%) [HD]

Permalink

Network

Neighborhood

Experiments

Cooccurrence

Databases

Coexpression

Textmining

Fusion

© STRING Consortium 2026

Credits

Access

Info

About