STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mafSeptum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (191 aa)    
Predicted Functional Partners:
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
   
  0.845
cmk
Cytidylate kinase; Identified by match to protein family HMM PF02224; match to protein family HMM TIGR00017.
    
  0.843
nrdD
Anaerobic ribonucleoside-triphosphate reductase; Identified by match to protein family HMM PF03477; match to protein family HMM TIGR02827.
     
  0.830
EFL45865.1
Identified by match to protein family HMM PF00149.
     
  0.830
EFL46685.1
Uracil phosphoribosyltransferase; Identified by match to protein family HMM PF00156.
     
  0.830
tdk
Thymidine kinase; Identified by match to protein family HMM PF00265.
     
  0.830
pyrH
UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
     
  0.830
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
     
  0.830
pyrF
Orotidine 5'-phosphate decarboxylase; Identified by match to protein family HMM PF00215; match to protein family HMM TIGR02127.
     
  0.830
udk
Uridine kinase; This gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF00485; match to protein family HMM TIGR00235.
    
  0.830
Your Current Organism:
Prevotella disiens
NCBI taxonomy Id: 866771
Other names: P. disiens FB035-09AN, Prevotella disiens FB035-09AN
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