STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFL47094.1Transcriptional regulator, AraC family; Identified by match to protein family HMM PF00165. (296 aa)    
Predicted Functional Partners:
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.764
nifJ
Pyruvate synthase; Identified by match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM TIGR02176.
     
 0.593
ribB
3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
 0.544
EFL45723.1
Malate dehydrogenase (oxaloacetate-decarboxylating); Identified by match to protein family HMM PF00390; match to protein family HMM PF01515; match to protein family HMM PF03949.
   
 
 0.524
EFL46248.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; This gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF02518.
  
 
 0.506
EFL46127.1
2-oxoacid:acceptor oxidoreductase, alpha subunit; Identified by match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM TIGR03710.
     
 0.493
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.480
EFL45735.1
Hypothetical protein.
  
 
   0.451
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
       0.426
EFL46886.1
Hypothetical protein.
  
     0.424
Your Current Organism:
Prevotella disiens
NCBI taxonomy Id: 866771
Other names: P. disiens FB035-09AN, Prevotella disiens FB035-09AN
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.