STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTCT_0621Conserved hypothetical protein. (318 aa)    
Predicted Functional Partners:
MTCT_0622
Conserved hypothetical protein.
 
  
 0.974
MTCT_1736
GTP-binding protein.
  
 0.803
dnaK
Chaperone DnaK; Acts as a chaperone.
  
 0.744
pan
Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...]
  
 
 0.702
asd-2
Phosphatidylserine decarboxylase; Catalyzes the formation of archaetidylethanolamine (PtdEtn) from archaetidylserine (PtdSer); Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
   
 
 0.636
MTCT_1653
Serine protease.
  
 
 0.626
MTCT_1349
Kinase.
  
 
 0.615
MTCT_1496
Cell division control protein.
   
 0.573
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
  
 0.568
MTCT_1087
Acetylpolyamine aminohydolase.
 
 
 0.566
Your Current Organism:
Methanothermobacter sp. CaT2
NCBI taxonomy Id: 866790
Other names: M. sp. CaT2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.