STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemCPorphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (289 aa)    
Predicted Functional Partners:
MTCT_0132
uroporphyrinogen-III synthase.
 0.999
MTCT_0665
Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 0.997
MTCT_0133
uroporphyrinogen-III methyltransferase; Belongs to the precorrin methyltransferase family.
  
 0.987
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
  
 0.984
MTCT_0793
Putative 3-chlorobenzoate-3,4-dioxygenase dyhydrogenase.
     
 0.955
MTCT_0794
Orotate phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
       0.943
hemL
Glutamate-1-semialdehyde aminotransferase.
 
  
 0.936
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydromethanopterin (H4MPT) serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro- aldol mechanism; Belongs to the SHMT family.
     
 0.827
MTCT_0910
Precorrin-6x reductase.
    
 0.823
MTCT_0791
Putative UDP-N-acetylmuramyl tripeptide synthetase.
     
 0.817
Your Current Organism:
Methanothermobacter sp. CaT2
NCBI taxonomy Id: 866790
Other names: M. sp. CaT2
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