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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SH3PXD2BSH3 and PX domains 2B. (906 aa)    
Predicted Functional Partners:
PAK2
P21 (RAC1) activated kinase 2.
    
 0.755
PAK6
P21 (RAC1) activated kinase 6.
    
 0.755
PAK1
P21 (RAC1) activated kinase 1.
    
 0.755
ENSPTXP00000007289
annotation not available
    
 0.755
ENSPTXP00000007297
annotation not available
    
 0.755
PAK3
P21 (RAC1) activated kinase 3.
    
 0.755
PAK4
P21 (RAC1) activated kinase 4.
    
 0.755
ARHGEF37
Rho guanine nucleotide exchange factor 37.
    
 0.746
TIAM1
TIAM Rac1 associated GEF 1.
    
 0.746
PREX1
Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1.
    
 0.746
Your Current Organism:
Pseudonaja textilis
NCBI taxonomy Id: 8673
Other names: MNHP 3944, P. textilis, eastern brown snake
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