close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRY4Sprouty RTK signaling antagonist 4. (297 aa)    
Predicted Functional Partners:
CBL
Cbl proto-oncogene.
    
 0.914
CBLB
Cbl proto-oncogene B.
    
 0.914
ENSPTXP00000027684
annotation not available
    
 0.914
GRB2
Growth factor receptor bound protein 2.
    
 0.818
GRAP2
GRB2 related adaptor protein 2.
    
 0.814
ENSPTXP00000004129
annotation not available
    
 0.814
SPRY1
Sprouty RTK signaling antagonist 1.
   
0.717
TESK1
Testis associated actin remodelling kinase 1.
    
 0.688
HBEGF
Heparin binding EGF like growth factor.
   
 
 0.677
BRAF
B-Raf proto-oncogene, serine/threonine kinase.
    
 0.662
Your Current Organism:
Pseudonaja textilis
NCBI taxonomy Id: 8673
Other names: MNHP 3944, P. textilis, eastern brown snake
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.