STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFL96922.1Hypothetical protein. (2361 aa)    
Predicted Functional Partners:
AFL96499.1
Hypothetical protein.
  
 
   0.996
AFL98022.1
Hypothetical protein.
  
 
 0.996
AFL98332.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.983
AFL97608.1
PFAM: Formylglycine-generating sulfatase enzyme; TIGRFAM: gliding motility-associated lipoprotein GldK.
 
   
 0.910
AFL97609.1
TIGRFAM: gliding motility-associated protein GldL.
  
   
 0.910
AFL96991.1
DNA polymerase elongation subunit (family B); PFAM: Predicted 3'-5' exonuclease related to the exonuclease domain of PolB.
  
 0.909
AFL96565.1
Hypothetical protein.
   
 0.892
AFL97610.1
PFAM: GldM C-terminal domain; GldM N-terminal domain; TIGRFAM: gliding motility-associated protein GldM.
  
   
 0.887
ruvA
Holliday junction DNA helicase subunit RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
  
  
 0.871
AFL96896.1
Protein involved in gliding motility SprE.
  
 
 0.866
Your Current Organism:
Ornithobacterium rhinotracheale
NCBI taxonomy Id: 867902
Other names: O. rhinotracheale DSM 15997, Ornithobacterium rhinotracheale DSM 15997, Ornithobacterium rhinotracheale LMG 9086, Ornithobacterium rhinotracheale str. DSM 15997, Ornithobacterium rhinotracheale strain DSM 15997
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