STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
AFL97450.12-oxoglutarate dehydrogenase complex dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (410 aa)    
Predicted Functional Partners:
AFL96261.1
Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit; PFAM: Dehydrogenase E1 component; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain.
 
 0.999
AFL97449.1
PFAM: Dehydrogenase E1 component; Transketolase, pyrimidine binding domain; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 component.
 0.999
AFL96721.1
Dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase.
 0.994
AFL98061.1
Dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase.
 0.991
AFL98136.1
Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 0.970
sucC
succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 
 0.969
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 
 0.966
AFL97939.1
2-oxoacid:acceptor oxidoreductase, alpha subunit; PFAM: domain; Transketolase, C-terminal domain; Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit.
     
 0.932
AFL98020.1
PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); e3 binding domain; Biotin-requiring enzyme; TIGRFAM: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase.
  
  
 
0.919
AFL96504.1
2-oxoacid:ferredoxin oxidoreductase, beta subunit; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain.
   
 
 0.907
Your Current Organism:
Ornithobacterium rhinotracheale
NCBI taxonomy Id: 867902
Other names: O. rhinotracheale DSM 15997, Ornithobacterium rhinotracheale DSM 15997, Ornithobacterium rhinotracheale LMG 9086, Ornithobacterium rhinotracheale str. DSM 15997, Ornithobacterium rhinotracheale strain DSM 15997
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