Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AGB48300.1TIGRFAM: signal peptidase I, archaeal type. (211 aa)    
Predicted Functional Partners:
AGB49940.1
Putative membrane-associated Zn-dependent protease.
 
  
 0.927
polB
Archaeal DNA polymerase II, small subunit/DNA polymerase delta, subunit B; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family.
       0.796
AGB48722.1
Putative membrane protein; TIGRFAM: exosortase/archaeosortase family protein; archaeosortase A, PGF-CTERM-specific.
  
   
 0.782
secD
Preprotein translocase subunit SecD; Involved in protein export.
 
  
 0.751
AGB48498.1
Putative membrane protein, required for N-linked glycosylation; TIGRFAM: oligosaccharyl transferase, archaeosortase system-associated.
 
  
 0.729
AGB50227.1
Hypothetical protein.
 
     0.711
atpE
Archaeal/vacuolar-type H+-ATPase subunit E; Produces ATP from ADP in the presence of a proton gradient across the membrane.
 
  
 0.706
AGB48560.1
Prepilin signal peptidase PulO-like peptidase.
 
   
 0.689
AGB48749.1
Putative membrane protein, required for N-linked glycosylation; TIGRFAM: oligosaccharyl transferase, archaeosortase system-associated.
 
  
 0.680
AGB48769.1
Archaeal flagellin-like protein; TIGRFAM: archaeal flagellin N-terminal-like domain.
  
     0.680
Your Current Organism:
Methanomethylovorans hollandica
NCBI taxonomy Id: 867904
Other names: M. hollandica DSM 15978, Methanomethylovorans hollandica DMS1, Methanomethylovorans hollandica DSM 15978, Methanomethylovorans hollandica str. DSM 15978, Methanomethylovorans hollandica strain DSM 15978
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