| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGB48516.1 | AGB48517.1 | Metho_0238 | Metho_0239 | 4-hydroxybenzoate polyprenyltransferase-like prenyltransferase. | Flavin-dependent dehydrogenase. | 0.958 |
| AGB48516.1 | AGB48518.1 | Metho_0238 | Metho_0240 | 4-hydroxybenzoate polyprenyltransferase-like prenyltransferase. | Putative Fe-S oxidoreductase. | 0.952 |
| AGB48516.1 | tgtA | Metho_0238 | Metho_0237 | 4-hydroxybenzoate polyprenyltransferase-like prenyltransferase. | tRNA-guanine transglycosylase, archaeosine-15-forming; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. | 0.883 |
| AGB48517.1 | AGB48516.1 | Metho_0239 | Metho_0238 | Flavin-dependent dehydrogenase. | 4-hydroxybenzoate polyprenyltransferase-like prenyltransferase. | 0.958 |
| AGB48517.1 | AGB48518.1 | Metho_0239 | Metho_0240 | Flavin-dependent dehydrogenase. | Putative Fe-S oxidoreductase. | 0.938 |
| AGB48517.1 | AGB48602.1 | Metho_0239 | Metho_0329 | Flavin-dependent dehydrogenase. | Phosphoglycerol geranylgeranyltransferase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | 0.435 |
| AGB48517.1 | AGB48611.1 | Metho_0239 | Metho_0338 | Flavin-dependent dehydrogenase. | 4-hydroxybenzoate polyprenyltransferase-like prenyltransferase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | 0.956 |
| AGB48517.1 | AGB48827.1 | Metho_0239 | Metho_0562 | Flavin-dependent dehydrogenase. | Mg chelatase, cobalamin biosynthesis protein CobN. | 0.480 |
| AGB48517.1 | AGB48828.1 | Metho_0239 | Metho_0563 | Flavin-dependent dehydrogenase. | Mg chelatase, cobalamin biosynthesis protein CobN. | 0.471 |
| AGB48517.1 | AGB48829.1 | Metho_0239 | Metho_0564 | Flavin-dependent dehydrogenase. | Mg chelatase, cobalamin biosynthesis protein CobN. | 0.474 |
| AGB48517.1 | AGB49617.1 | Metho_0239 | Metho_1408 | Flavin-dependent dehydrogenase. | 4-hydroxybenzoate polyprenyltransferase-like prenyltransferase. | 0.942 |
| AGB48517.1 | carS | Metho_0239 | Metho_1973 | Flavin-dependent dehydrogenase. | CDP-diglyceride synthetase; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | 0.914 |
| AGB48517.1 | tgtA | Metho_0239 | Metho_0237 | Flavin-dependent dehydrogenase. | tRNA-guanine transglycosylase, archaeosine-15-forming; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. | 0.876 |
| AGB48518.1 | AGB48516.1 | Metho_0240 | Metho_0238 | Putative Fe-S oxidoreductase. | 4-hydroxybenzoate polyprenyltransferase-like prenyltransferase. | 0.952 |
| AGB48518.1 | AGB48517.1 | Metho_0240 | Metho_0239 | Putative Fe-S oxidoreductase. | Flavin-dependent dehydrogenase. | 0.938 |
| AGB48518.1 | tgtA | Metho_0240 | Metho_0237 | Putative Fe-S oxidoreductase. | tRNA-guanine transglycosylase, archaeosine-15-forming; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. | 0.830 |
| AGB48602.1 | AGB48517.1 | Metho_0329 | Metho_0239 | Phosphoglycerol geranylgeranyltransferase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | Flavin-dependent dehydrogenase. | 0.435 |
| AGB48602.1 | AGB48611.1 | Metho_0329 | Metho_0338 | Phosphoglycerol geranylgeranyltransferase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | 4-hydroxybenzoate polyprenyltransferase-like prenyltransferase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | 0.983 |
| AGB48602.1 | AGB49617.1 | Metho_0329 | Metho_1408 | Phosphoglycerol geranylgeranyltransferase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | 4-hydroxybenzoate polyprenyltransferase-like prenyltransferase. | 0.975 |
| AGB48602.1 | carS | Metho_0329 | Metho_1973 | Phosphoglycerol geranylgeranyltransferase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | CDP-diglyceride synthetase; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | 0.660 |