Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AGB49134.1Hypothetical protein. (291 aa)    
Predicted Functional Partners:
AGB49133.1
Putative RNA-binding protein.
       0.890
gap
TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type II.
       0.569
AGB49131.1
Inositol monophosphatase/fructose-1,6-bisphosphatase family protein.
 
     0.567
nadK
Putative sugar kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
 
     0.566
AGB49284.1
metal-binding-domain/4Fe-4S-binding-domain containing ABC transporter, ATP-binding protein; TIGRFAM: MJ0570-related uncharacterized domain; TIGR00289 family protein; asparagine synthase (glutamine-hydrolyzing); arCOG00187 universal archaeal metal-binding-domain/4Fe-4S-binding-domain containing ABC transporter, ATP-binding protein.
     
 0.541
AGB49135.1
Putative membrane protein; TIGRFAM: TIGR00267 family protein.
       0.528
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
     
 0.510
AGB49136.1
TIGRFAM: K+-dependent Na+/Ca+ exchanger related-protein.
 
     0.479
AGB50294.1
P-loop ATPase, MinD superfamily.
 
     0.413
AGB50289.1
Metal-dependent hydrolase, beta-lactamase superfamily II.
 
     0.402
Your Current Organism:
Methanomethylovorans hollandica
NCBI taxonomy Id: 867904
Other names: M. hollandica DSM 15978, Methanomethylovorans hollandica DMS1, Methanomethylovorans hollandica DSM 15978, Methanomethylovorans hollandica str. DSM 15978, Methanomethylovorans hollandica strain DSM 15978
Server load: low (20%) [HD]