close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gmdGDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (325 aa)    
Predicted Functional Partners:
AGB48756.1
TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Belongs to the mannose-6-phosphate isomerase type 2 family.
 
 
 0.970
AGB48923.1
Nucleoside-diphosphate-sugar pyrophosphorylase family protein; TIGRFAM: glucose-1-phosphate thymidylylransferase, long form.
    
 0.920
AGB50151.1
TIGRFAM: UDP-N-acetylglucosamine 2-epimerase.
  
  
 0.630
AGB49508.1
ABC-type polysaccharide/polyol phosphate export systems, permease component.
 
  
 0.593
AGB49509.1
ABC-type polysaccharide/polyol phosphate transport system, ATPase component.
 
  
 0.593
AGB49913.1
Nucleoside-diphosphate-sugar epimerase.
 
 
 0.579
AGB50286.1
ATPase involved in chromosome partitioning; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
  
  
 0.557
AGB49982.1
Putative PLP-dependent enzyme possibly involved in cell wall biogenesis; Belongs to the DegT/DnrJ/EryC1 family.
  
  
 0.551
AGB49979.1
Nucleoside-diphosphate-sugar epimerase.
 
 
0.540
AGB49687.1
Nucleoside-diphosphate-sugar epimerase; Manually curated; non-canonical start codon.
  
 
0.523
Your Current Organism:
Methanomethylovorans hollandica
NCBI taxonomy Id: 867904
Other names: M. hollandica DSM 15978, Methanomethylovorans hollandica DMS1, Methanomethylovorans hollandica DSM 15978, Methanomethylovorans hollandica str. DSM 15978, Methanomethylovorans hollandica strain DSM 15978
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.