Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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uppSUndecaprenyl diphosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids. (295 aa)    
Predicted Functional Partners:
AGB49074.1
Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.
 
 
 0.981
AGB49825.1
Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.
 
 
 0.976
AGB50158.1
Protein of unknown function (DUF2551).
       0.849
AGB49940.1
Putative membrane-associated Zn-dependent protease.
 
  
 0.759
valS
valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
 
  
 0.746
AGB50157.1
Hypothetical protein.
       0.715
nusA
NusA family KH domain protein; Participates in transcription termination. Belongs to the NusA family.
 
    0.627
AGB48916.1
TIGRFAM: putative methanogen marker protein 4.
  
    0.595
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
 
  
 0.588
rps10
Ribosomal protein S10/S20; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
 
  
 0.560
Your Current Organism:
Methanomethylovorans hollandica
NCBI taxonomy Id: 867904
Other names: M. hollandica DSM 15978, Methanomethylovorans hollandica DMS1, Methanomethylovorans hollandica DSM 15978, Methanomethylovorans hollandica str. DSM 15978, Methanomethylovorans hollandica strain DSM 15978
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