| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGB48395.1 | AGB48503.1 | Metho_0106 | Metho_0220 | Hypothetical protein. | DNA polymerase elongation subunit (family B). | 0.910 |
| AGB48395.1 | AGB50332.1 | Metho_0106 | Metho_2169 | Hypothetical protein. | Orc1/cdc6 family replication initiation protein; Involved in regulation of DNA replication. | 0.883 |
| AGB48395.1 | pcn | Metho_0106 | Metho_0458 | Hypothetical protein. | Proliferating cell nuclear antigen PCNA; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. | 0.658 |
| AGB48395.1 | priL | Metho_0106 | Metho_0459 | Hypothetical protein. | DNA primase, large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. | 0.932 |
| AGB48395.1 | priS | Metho_0106 | Metho_0403 | Hypothetical protein. | DNA primase, eukaryotic-type, small subunit, putative; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extens [...] | 0.906 |
| AGB48503.1 | AGB48395.1 | Metho_0220 | Metho_0106 | DNA polymerase elongation subunit (family B). | Hypothetical protein. | 0.910 |
| AGB48503.1 | AGB49043.1 | Metho_0220 | Metho_0796 | DNA polymerase elongation subunit (family B). | Putative ATPase involved in replication control, Cdc46/Mcm family; Belongs to the MCM family. | 0.945 |
| AGB48503.1 | AGB50332.1 | Metho_0220 | Metho_2169 | DNA polymerase elongation subunit (family B). | Orc1/cdc6 family replication initiation protein; Involved in regulation of DNA replication. | 0.707 |
| AGB48503.1 | dnaG | Metho_0220 | Metho_2413 | DNA polymerase elongation subunit (family B). | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | 0.565 |
| AGB48503.1 | pcn | Metho_0220 | Metho_0458 | DNA polymerase elongation subunit (family B). | Proliferating cell nuclear antigen PCNA; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. | 0.992 |
| AGB48503.1 | polB | Metho_0220 | Metho_0003 | DNA polymerase elongation subunit (family B). | Archaeal DNA polymerase II, small subunit/DNA polymerase delta, subunit B; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family. | 0.984 |
| AGB48503.1 | priL | Metho_0220 | Metho_0459 | DNA polymerase elongation subunit (family B). | DNA primase, large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. | 0.987 |
| AGB48503.1 | priS | Metho_0220 | Metho_0403 | DNA polymerase elongation subunit (family B). | DNA primase, eukaryotic-type, small subunit, putative; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extens [...] | 0.988 |
| AGB48503.1 | radA | Metho_0220 | Metho_2285 | DNA polymerase elongation subunit (family B). | DNA repair and recombination protein RadA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. | 0.859 |
| AGB49043.1 | AGB48503.1 | Metho_0796 | Metho_0220 | Putative ATPase involved in replication control, Cdc46/Mcm family; Belongs to the MCM family. | DNA polymerase elongation subunit (family B). | 0.945 |
| AGB49043.1 | AGB50332.1 | Metho_0796 | Metho_2169 | Putative ATPase involved in replication control, Cdc46/Mcm family; Belongs to the MCM family. | Orc1/cdc6 family replication initiation protein; Involved in regulation of DNA replication. | 0.923 |
| AGB49043.1 | pcn | Metho_0796 | Metho_0458 | Putative ATPase involved in replication control, Cdc46/Mcm family; Belongs to the MCM family. | Proliferating cell nuclear antigen PCNA; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. | 0.843 |
| AGB49043.1 | polB | Metho_0796 | Metho_0003 | Putative ATPase involved in replication control, Cdc46/Mcm family; Belongs to the MCM family. | Archaeal DNA polymerase II, small subunit/DNA polymerase delta, subunit B; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family. | 0.485 |
| AGB49043.1 | priL | Metho_0796 | Metho_0459 | Putative ATPase involved in replication control, Cdc46/Mcm family; Belongs to the MCM family. | DNA primase, large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. | 0.932 |
| AGB49043.1 | priS | Metho_0796 | Metho_0403 | Putative ATPase involved in replication control, Cdc46/Mcm family; Belongs to the MCM family. | DNA primase, eukaryotic-type, small subunit, putative; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extens [...] | 0.922 |
