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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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[Homology]
Score
AGB50535.1acetate--CoA ligase; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme; TIGRFAM: acetate--CoA ligase. (628 aa)    
Predicted Functional Partners:
AGB48850.1
TIGRFAM: acetyl coenzyme A synthetase (ADP forming), alpha domain.
 
  
 0.964
AGB50524.1
acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain.
  
 
 0.956
AGB49347.1
Citrate synthase.
  
 0.943
cdhD
CO dehydrogenase/acetyl-CoA synthase, delta subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. Probably maintains the overall quaternary structure of the ACDS complex.
  
 
 0.926
AGB50580.1
PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family.
  
 
 0.925
cdhC
CO dehydrogenase/CO-methylating acetyl-CoA synthase complex, beta subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron- sulfur protein (the gamma-delta complex).
  
 
 0.924
cdhE
CO dehydrogenase/acetyl-CoA synthase gamma subunit (corrinoid Fe-S protein); Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy.
  
 
 0.924
AGB50213.1
acyl-CoA synthetase/AMP-acid ligase.
 
 
0.924
AGB48630.1
NAD-dependent aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.923
AGB49556.1
TIGRFAM: DNA binding domain, excisionase family.
 
 
0.923
Your Current Organism:
Methanomethylovorans hollandica
NCBI taxonomy Id: 867904
Other names: M. hollandica DSM 15978, Methanomethylovorans hollandica DMS1, Methanomethylovorans hollandica DSM 15978, Methanomethylovorans hollandica str. DSM 15978, Methanomethylovorans hollandica strain DSM 15978
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