node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AEG17278.1 | AEG18771.1 | MSWAN_0232 | MSWAN_1760 | DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | TIGRFAM: DNA-directed RNA polymerase; KEGG: mmg:MTBMA_c07140 DNA-directed RNA polymerase subunit E'; PFAM: RNA polymerase Rpb7, N-terminal; Ribosomal protein S1, RNA binding domain. | 0.999 |
AEG17278.1 | AEG19420.1 | MSWAN_0232 | MSWAN_2418 | DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | 0.490 |
AEG17278.1 | eif2g | MSWAN_0232 | MSWAN_1757 | DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Translation initiation factor 2 subunit gamma; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. | 0.703 |
AEG17278.1 | rpoA2 | MSWAN_0232 | MSWAN_0233 | DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase subunit A'; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
AEG17278.1 | rps6e | MSWAN_0232 | MSWAN_1756 | DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | KEGG: mth:MTH260 30S ribosomal protein S6e; HAMAP: 30S ribosomal protein S6e; PFAM: Ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family. | 0.521 |
AEG17278.1 | spt4 | MSWAN_0232 | MSWAN_1761 | DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase subunit E, RpoE2; Stimulates transcription elongation; Belongs to the archaeal Spt4 family. | 0.872 |
AEG17278.1 | spt5 | MSWAN_0232 | MSWAN_0395 | DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | NusG antitermination factor; Stimulates transcription elongation; Belongs to the archaeal Spt5 family. | 0.928 |
AEG18771.1 | AEG17278.1 | MSWAN_1760 | MSWAN_0232 | TIGRFAM: DNA-directed RNA polymerase; KEGG: mmg:MTBMA_c07140 DNA-directed RNA polymerase subunit E'; PFAM: RNA polymerase Rpb7, N-terminal; Ribosomal protein S1, RNA binding domain. | DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
AEG18771.1 | AEG18773.1 | MSWAN_1760 | MSWAN_1762 | TIGRFAM: DNA-directed RNA polymerase; KEGG: mmg:MTBMA_c07140 DNA-directed RNA polymerase subunit E'; PFAM: RNA polymerase Rpb7, N-terminal; Ribosomal protein S1, RNA binding domain. | UPF0218 protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). | 0.979 |
AEG18771.1 | AEG19420.1 | MSWAN_1760 | MSWAN_2418 | TIGRFAM: DNA-directed RNA polymerase; KEGG: mmg:MTBMA_c07140 DNA-directed RNA polymerase subunit E'; PFAM: RNA polymerase Rpb7, N-terminal; Ribosomal protein S1, RNA binding domain. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | 0.932 |
AEG18771.1 | eif2g | MSWAN_1760 | MSWAN_1757 | TIGRFAM: DNA-directed RNA polymerase; KEGG: mmg:MTBMA_c07140 DNA-directed RNA polymerase subunit E'; PFAM: RNA polymerase Rpb7, N-terminal; Ribosomal protein S1, RNA binding domain. | Translation initiation factor 2 subunit gamma; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. | 0.788 |
AEG18771.1 | rpoA2 | MSWAN_1760 | MSWAN_0233 | TIGRFAM: DNA-directed RNA polymerase; KEGG: mmg:MTBMA_c07140 DNA-directed RNA polymerase subunit E'; PFAM: RNA polymerase Rpb7, N-terminal; Ribosomal protein S1, RNA binding domain. | DNA-directed RNA polymerase subunit A'; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
AEG18771.1 | rps24e | MSWAN_1760 | MSWAN_1763 | TIGRFAM: DNA-directed RNA polymerase; KEGG: mmg:MTBMA_c07140 DNA-directed RNA polymerase subunit E'; PFAM: RNA polymerase Rpb7, N-terminal; Ribosomal protein S1, RNA binding domain. | KEGG: mmg:MTBMA_c07170 30S ribosomal protein S24e; HAMAP: 30S ribosomal protein S24e; PFAM: Ribosomal protein S24e; Belongs to the eukaryotic ribosomal protein eS24 family. | 0.958 |
AEG18771.1 | rps27ae | MSWAN_1760 | MSWAN_1764 | TIGRFAM: DNA-directed RNA polymerase; KEGG: mmg:MTBMA_c07140 DNA-directed RNA polymerase subunit E'; PFAM: RNA polymerase Rpb7, N-terminal; Ribosomal protein S1, RNA binding domain. | KEGG: mst:Msp_0620 30S ribosomal protein S27ae; HAMAP: 30S ribosomal protein S27ae; PFAM: Ribosomal protein S27a; Belongs to the eukaryotic ribosomal protein eS31 family. | 0.891 |
AEG18771.1 | rps6e | MSWAN_1760 | MSWAN_1756 | TIGRFAM: DNA-directed RNA polymerase; KEGG: mmg:MTBMA_c07140 DNA-directed RNA polymerase subunit E'; PFAM: RNA polymerase Rpb7, N-terminal; Ribosomal protein S1, RNA binding domain. | KEGG: mth:MTH260 30S ribosomal protein S6e; HAMAP: 30S ribosomal protein S6e; PFAM: Ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family. | 0.790 |
AEG18771.1 | spt4 | MSWAN_1760 | MSWAN_1761 | TIGRFAM: DNA-directed RNA polymerase; KEGG: mmg:MTBMA_c07140 DNA-directed RNA polymerase subunit E'; PFAM: RNA polymerase Rpb7, N-terminal; Ribosomal protein S1, RNA binding domain. | DNA-directed RNA polymerase subunit E, RpoE2; Stimulates transcription elongation; Belongs to the archaeal Spt4 family. | 0.998 |
AEG18771.1 | spt5 | MSWAN_1760 | MSWAN_0395 | TIGRFAM: DNA-directed RNA polymerase; KEGG: mmg:MTBMA_c07140 DNA-directed RNA polymerase subunit E'; PFAM: RNA polymerase Rpb7, N-terminal; Ribosomal protein S1, RNA binding domain. | NusG antitermination factor; Stimulates transcription elongation; Belongs to the archaeal Spt5 family. | 0.664 |
AEG18773.1 | AEG18771.1 | MSWAN_1762 | MSWAN_1760 | UPF0218 protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). | TIGRFAM: DNA-directed RNA polymerase; KEGG: mmg:MTBMA_c07140 DNA-directed RNA polymerase subunit E'; PFAM: RNA polymerase Rpb7, N-terminal; Ribosomal protein S1, RNA binding domain. | 0.979 |
AEG18773.1 | AEG19420.1 | MSWAN_1762 | MSWAN_2418 | UPF0218 protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | 0.921 |
AEG18773.1 | eif2g | MSWAN_1762 | MSWAN_1757 | UPF0218 protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). | Translation initiation factor 2 subunit gamma; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. | 0.643 |