Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEF93005.1Transcriptional regulator, AbrB family; TIGRFAM: Sporulation stage V, protein T; Transcription regulator AbrB; PFAM: Transcription regulator AbrB/SpoV, predicted; GAF; KEGG: drm:Dred_0113 AbrB family transcriptional regulator; SMART: Transcription regulator AbrB/SpoV, predicted. (186 aa)    
Predicted Functional Partners:
AEF95442.1
TIGRFAM: Sporulation stage III, transcriptional regulator SpoIIID; KEGG: drm:Dred_3145 regulatory protein, DeoR.
  
  
 0.870
AEF95286.1
Stage II sporulation protein R; KEGG: drm:Dred_0458 pro-sigma-E processing factor spoIIR; TIGRFAM: Sporulation stage II, protein R; PFAM: Sporulation stage II, protein R.
  
   
 0.846
spoIIAB
Anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
   
 0.836
AEF94930.1
Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.836
AEF94964.1
Stage III sporulation protein AA; KEGG: drm:Dred_1056 hypothetical protein; TIGRFAM: Sporulation stage III, protein AA; SMART: ATPase, AAA+ type, core.
  
   
 0.828
AEF93835.1
KEGG: drm:Dred_1464 stage V sporulation protein AD; TIGRFAM: Stage V sporulation AD; PFAM: Stage V sporulation AD.
  
   
 0.827
AEF93010.1
KEGG: drm:Dred_0118 YabP family protein; TIGRFAM: Sporulation protein YabP; PFAM: Sporulation protein YabP/YqfC.
 
     0.819
AEF95163.1
RNA polymerase, sigma 28 subunit, SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
   
 0.804
AEF94843.1
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
  
 0.797
AEF93016.1
SMART: Protein phosphatase 2C-like; TIGRFAM: Sporulation stage II, protein E; KEGG: drm:Dred_0124 phosphoprotein phosphatase; PFAM: Sporulation stage II, protein E C-terminal.
 
   
 0.790
Your Current Organism:
Desulfotomaculum nigrificans
NCBI taxonomy Id: 868595
Other names: D. nigrificans CO-1-SRB, Desulfotomaculum carboxydivorans CO-1-SRB, Desulfotomaculum carboxydivorans DSM 14880, Desulfotomaculum nigrificans CO-1-SRB
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