STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEF93207.1Metallophosphoesterase; PFAM: Metallo-dependent phosphatase; KEGG: dae:Dtox_2833 metallophosphoesterase. (347 aa)    
Predicted Functional Partners:
AEF93295.1
Ankyrin; KEGG: aag:AaeL_AAEL004651 multiple ankyrin repeats single kh domain protein; PFAM: Ankyrin repeat; SMART: Ankyrin repeat.
   
 
 0.840
AEF94381.1
Multi-sensor hybrid histidine kinase; TIGRFAM: PAS; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold-4; PAS fold; Signal transduction response regulator, receiver domain; Signal transduction histidine kinase, phosphotransfer (Hpt) domain; KEGG: drm:Dred_2145 multi-sensor hybrid histidine kinase; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS; Signal transduction response regulator, receiver domain.
  
  
 0.585
AEF93208.1
PFAM: Alkaline phosphatase; KEGG: ppm:PPSC2_c3050 alkaline phosphatase III; SMART: Alkaline phosphatase; Belongs to the alkaline phosphatase family.
  
  
 0.450
AEF94879.1
CBS domain containing protein; KEGG: drm:Dred_1131 polynucleotide adenylyltransferase region; PFAM: Cystathionine beta-synthase, core; Phosphoesterase, RecJ-like; Phosphoesterase, DHHA1; Poly A polymerase, head domain; SMART: Cystathionine beta-synthase, core; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
     
 0.449
AEF93759.1
PFAM: Glycosyl transferase, family 2; Glycosyl transferase, group 1; KEGG: glo:Glov_3374 glycosyl transferase family 2.
  
  
 0.444
AEF93764.1
PFAM: Glycosyl transferase, family 2; KEGG: nde:NIDE2334 hypothetical protein.
  
 
 0.442
hisI
PFAM: Phosphoribosyl-AMP cyclohydrolase; Phosphoribosyl-ATP pyrophosphohydrolase-like; TIGRFAM: Phosphoribosyl-ATP pyrophosphohydrolase; HAMAP: Phosphoribosyl-ATP pyrophosphohydrolase; Histidine biosynthesis bifunctional protein HisIE; KEGG: drm:Dred_2349 phosphoribosyl-AMP cyclohydrolase; In the N-terminal section; belongs to the PRA-CH family.
     
 0.440
cinA
TIGRFAM: Competence-induced protein CinA; CinA, C-terminal; PFAM: CinA, C-terminal; Molybdopterin binding; KEGG: drm:Dred_1922 competence damage-inducible protein A; SMART: Molybdopterin binding; Belongs to the CinA family.
  
    0.425
nnrD
YjeF-related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...]
       0.402
AEF93548.1
TIGRFAM: Diguanylate cyclase, predicted; PFAM: Diguanylate cyclase, predicted; GAF; Metal-dependent phosphohydrolase, HD subdomain; KEGG: pth:PTH_0310 HD-GYP domain-containing protein; SMART: Diguanylate cyclase, predicted; GAF.
  
  
 0.400
Your Current Organism:
Desulfotomaculum nigrificans
NCBI taxonomy Id: 868595
Other names: D. nigrificans CO-1-SRB, Desulfotomaculum carboxydivorans CO-1-SRB, Desulfotomaculum carboxydivorans DSM 14880, Desulfotomaculum nigrificans CO-1-SRB
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