STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEF93298.1PFAM: NUDIX hydrolase domain; KEGG: drm:Dred_1568 NUDIX hydrolase. (222 aa)    
Predicted Functional Partners:
nnrD
YjeF-related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...]
  
 0.995
AEF94309.1
KEGG: drm:Dred_1921 DEAD/DEAH box helicase domain-containing protein; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; DbpA, RNA-binding; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal; Belongs to the DEAD box helicase family.
   
 0.964
rph
Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
    
 0.866
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
   
    0.772
AEF93296.1
Transcriptional regulator, PadR-like family; PFAM: Transcription regulator PadR N-terminal-like; KEGG: dau:Daud_0311 PadR-like family transcriptional regulator.
     
 0.684
AEF93297.1
PFAM: Bacterial extracellular solute-binding, family 1; KEGG: dau:Daud_0310 ABC-transporter-like protein, periplasmic substrate-binding protein.
     
 0.683
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
   
 
 0.672
AEF95527.1
TIGRFAM: HAD-superfamily hydrolase, subfamily IIA; KEGG: clj:CLJU_c33070 hypothetical protein; PFAM: NUDIX hydrolase domain; Haloacid dehalogenase-like hydrolase.
  
  
 0.625
AEF94337.1
KEGG: drm:Dred_1947 peptidase M16 domain-containing protein; PFAM: Peptidase M16, N-terminal; Peptidase M16, C-terminal; Belongs to the peptidase M16 family.
   
   0.562
AEF93295.1
Ankyrin; KEGG: aag:AaeL_AAEL004651 multiple ankyrin repeats single kh domain protein; PFAM: Ankyrin repeat; SMART: Ankyrin repeat.
   
 
 0.515
Your Current Organism:
Desulfotomaculum nigrificans
NCBI taxonomy Id: 868595
Other names: D. nigrificans CO-1-SRB, Desulfotomaculum carboxydivorans CO-1-SRB, Desulfotomaculum carboxydivorans DSM 14880, Desulfotomaculum nigrificans CO-1-SRB
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