STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ureBPFAM: Urease, beta subunit; TIGRFAM: Urease, beta subunit; HAMAP: Urease, beta subunit; KEGG: tjr:TherJR_0606 urease, beta subunit. (124 aa)    
Predicted Functional Partners:
ureA
PFAM: Urease, alpha/gamma subunit; TIGRFAM: Urease, alpha/gamma subunit; HAMAP: Urease, gamma subunit; KEGG: tjr:TherJR_0605 urease, gamma subunit.
 0.999
ureC
PFAM: Amidohydrolase 1; Urease alpha-subunit, N-terminal; TIGRFAM: Urease, alpha subunit; HAMAP: Urease, alpha subunit; KEGG: tjr:TherJR_0607 urease, alpha subunit.
 0.999
ureF
Urease accessory protein ureF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.988
ureD
Urease accessory protein ureD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.986
ureE
Urease accessory protein ureE; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.
 
  
 0.984
ureG
Urease accessory protein ureG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
 
  
 0.963
AEF93626.1
TIGRFAM: ABC transporter, urea, ATP-binding protein, UrtD; KEGG: pjd:Pjdr2_0560 UreA ABC transporter, ATP-binding protein UrtD; PFAM: ABC transporter-like.
     
 0.678
AEF93247.1
KEGG: mta:Moth_2180 hydrogenase accessory protein HypB; TIGRFAM: Hydrogenase accessory protein HypB; PFAM: Cobalamin (vitamin B12) biosynthesis CobW-like.
  
  
 0.676
AEF93627.1
SMART: ATPase, AAA+ type, core; TIGRFAM: ABC transporter, urea, ATP-binding protein, UrtE; KEGG: tel:tlr1124 putative branched chain ABC transporter ATP-binding protein; PFAM: ABC transporter-like.
     
 0.637
AEF93625.1
KEGG: cth:Cthe_1821 inner-membrane translocator; TIGRFAM: ABC transporter, urea, permease protein, UrtC; PFAM: ABC transporter permease.
     
 0.616
Your Current Organism:
Desulfotomaculum nigrificans
NCBI taxonomy Id: 868595
Other names: D. nigrificans CO-1-SRB, Desulfotomaculum carboxydivorans CO-1-SRB, Desulfotomaculum carboxydivorans DSM 14880, Desulfotomaculum nigrificans CO-1-SRB
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