STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEF93895.1Sporulation protein YtaF; Probably functions as a manganese efflux pump. (214 aa)    
Predicted Functional Partners:
coaE
Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
  
    0.916
mutM
Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
  
    0.771
AEF94902.1
PFAM: Bacillus/Clostridium GerA spore germination protein; KEGG: drm:Dred_1110 GerA spore germination protein.
  
     0.684
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
    0.676
AEF93010.1
KEGG: drm:Dred_0118 YabP family protein; TIGRFAM: Sporulation protein YabP; PFAM: Sporulation protein YabP/YqfC.
  
   
 0.674
AEF94333.1
KEGG: drm:Dred_1943 dipicolinate synthase subunit A; TIGRFAM: Dipicolinic acid synthetase, subunit A; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding.
  
     0.672
AEF93893.1
PFAM: Lytic transglycosylase-like, catalytic; KEGG: drm:Dred_1595 lytic transglycosylase, catalytic.
       0.669
AEF95073.1
KEGG: drm:Dred_0767 hypothetical protein.
  
     0.617
AEF94850.1
KEGG: drm:Dred_1157 hypothetical protein.
  
     0.598
AEF94931.1
Stage IV sporulation protein B; SMART: PDZ/DHR/GLGF; TIGRFAM: Peptidase S55, sporulation stage IV, protein B; KEGG: drm:Dred_1085 peptidase S55, SpoIVB; PFAM: Peptidase S55, SpoIVB; PDZ/DHR/GLGF.
  
     0.588
Your Current Organism:
Desulfotomaculum nigrificans
NCBI taxonomy Id: 868595
Other names: D. nigrificans CO-1-SRB, Desulfotomaculum carboxydivorans CO-1-SRB, Desulfotomaculum carboxydivorans DSM 14880, Desulfotomaculum nigrificans CO-1-SRB
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