Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AEF93898.1Carboxyl-terminal protease; TIGRFAM: Peptidase S41A, C-terminal peptidase; PFAM: Peptidase S41; PDZ/DHR/GLGF; Copper amine oxidase-like, N-terminal; KEGG: drm:Dred_1600 carboxyl-terminal protease; SMART: Peptidase S41; PDZ/DHR/GLGF. (491 aa)    
Predicted Functional Partners:
AEF93759.1
PFAM: Glycosyl transferase, family 2; Glycosyl transferase, group 1; KEGG: glo:Glov_3374 glycosyl transferase family 2.
  
 
 0.651
AEF95319.1
KEGG: dsy:DSY0661 hypothetical protein; TIGRFAM: Conserved hypothetical protein CHP02677; PFAM: Conserved hypothetical protein CHP02677.
  
 
 0.617
AEF93899.1
SNARE associated Golgi protein; KEGG: drm:Dred_1601 hypothetical protein; manually curated; PFAM: SNARE associated Golgi protein.
       0.590
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
     0.550
AEF94359.1
TIGRFAM: Peptidase M50, putative membrane-associated zinc metallopeptidase; PFAM: Peptidase M50; KEGG: drm:Dred_1969 putative membrane-associated zinc metalloprotease; SMART: PDZ/DHR/GLGF.
 
  
 0.537
AEF94956.1
TIGRFAM: Acetyl-CoA biotin carboxyl carrier; KEGG: drm:Dred_1064 pyruvate carboxylase subunit B; PFAM: Carboxylase, conserved domain; Pyruvate carboxyltransferase; Biotin/lipoyl attachment.
   
    0.512
AEF93765.1
KEGG: drm:Dred_1385 glycosyl transferase family protein; PFAM: Glycosyl transferase, family 2; SMART: Tetratricopeptide repeat.
  
 
 0.468
mutM
Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
       0.419
AEF93769.1
KEGG: drm:Dred_1410 glycosyl transferase family protein.
  
 
 0.402
AEF93770.1
KEGG: drm:Dred_1410 glycosyl transferase family protein; PFAM: Glycosyl transferase, family 2; Tetratricopeptide TPR-1; SMART: Tetratricopeptide repeat.
  
 
 0.402
Your Current Organism:
Desulfotomaculum nigrificans
NCBI taxonomy Id: 868595
Other names: D. nigrificans CO-1-SRB, Desulfotomaculum carboxydivorans CO-1-SRB, Desulfotomaculum carboxydivorans DSM 14880, Desulfotomaculum nigrificans CO-1-SRB
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