Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEF94752.1Monosaccharide-transporting ATPase; PFAM: ABC transporter-like; KEGG: drm:Dred_2524 ABC transporter related; SMART: ATPase, AAA+ type, core. (498 aa)    
Predicted Functional Partners:
AEF94751.1
ABC-type transporter, integral membrane subunit; PFAM: ABC transporter permease; KEGG: drm:Dred_2523 inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family.
 0.999
AEF94750.1
PFAM: Periplasmic binding protein/LacI transcriptional regulator; KEGG: hmo:HM1_2420 ribose abc transporter, ribose-binding protein.
 
 0.997
rbsD
D-ribose pyranase; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
 
  
 0.995
rbsK
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
 
  
 0.994
AEF93847.1
KEGG: drm:Dred_1473 ABC-type sugar transport system periplasmic component-like protein.
 
 
 0.953
AEF94755.1
KEGG: aac:Aaci_2281 transcriptional regulator, LacI family; PFAM: Periplasmic binding protein/LacI transcriptional regulator; HTH transcriptional regulator, LacI; SMART: HTH transcriptional regulator, LacI.
 
  
 0.927
AEF94381.1
Multi-sensor hybrid histidine kinase; TIGRFAM: PAS; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold-4; PAS fold; Signal transduction response regulator, receiver domain; Signal transduction histidine kinase, phosphotransfer (Hpt) domain; KEGG: drm:Dred_2145 multi-sensor hybrid histidine kinase; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS; Signal transduction response regulator, receiver domain.
   
  
 0.444
AEF95518.1
KEGG: mta:Moth_0013 PTS fructose IIC component; TIGRFAM: Phosphotransferase system, fructose IIC component; Phosphotransferase system, fructose-specific IIB subunit; PFAM: Phosphotransferase system, EIIC.
      
 0.442
metG
Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
   
   0.422
AEF93412.1
KEGG: drm:Dred_2805 glutamate synthase (ferredoxin); PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal.
      
 0.422
Your Current Organism:
Desulfotomaculum nigrificans
NCBI taxonomy Id: 868595
Other names: D. nigrificans CO-1-SRB, Desulfotomaculum carboxydivorans CO-1-SRB, Desulfotomaculum carboxydivorans DSM 14880, Desulfotomaculum nigrificans CO-1-SRB
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