Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEF94767.1KEGG: toc:Toce_0380 hypothetical protein. (473 aa)    
Predicted Functional Partners:
AEF94768.1
PFAM: 4Fe-4S binding domain; BFD-like [2Fe-2S]-binding domain; KEGG: toc:Toce_0379 BFD domain protein (2Fe-2S)-binding domain protein.
       0.822
AEF94770.1
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
       0.819
AEF94769.1
4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
       0.777
AEF94771.1
2-oxopent-4-enoate hydratase; KEGG: mta:Moth_1777 4-oxalocrotonate decarboxylase; PFAM: Fumarylacetoacetase, C-terminal-like.
       0.770
AEF94773.1
PFAM: Quinolinate phosphoribosyl transferase, N-terminal; Ribulose-phosphate 3-epimerase; KEGG: mta:Moth_1779 nicotinate-nucleotide pyrophosphorylase.
       0.769
AEF94772.1
KEGG: mta:Moth_1778 molybdopterin binding domain-containing protein; PFAM: Molybdopterin binding; SMART: Molybdopterin binding.
       0.726
AEF94774.1
KEGG: toc:Toce_0385 transcriptional regulator, IclR family; PFAM: Transcription regulator IclR, C-terminal; Transcription regulator IclR, N-terminal; SMART: Transcription regulator IclR, N-terminal.
       0.724
AEF94766.1
KEGG: chy:CHY_1271 putative benzoate transporter; TIGRFAM: Benzoate membrane transport protein; PFAM: Benzoate membrane transport protein.
       0.580
Your Current Organism:
Desulfotomaculum nigrificans
NCBI taxonomy Id: 868595
Other names: D. nigrificans CO-1-SRB, Desulfotomaculum carboxydivorans CO-1-SRB, Desulfotomaculum carboxydivorans DSM 14880, Desulfotomaculum nigrificans CO-1-SRB
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