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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
AEF94807.1Indolepyruvate ferredoxin oxidoreductase, alpha subunit; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates. (600 aa)    
Predicted Functional Partners:
AEF94806.1
KEGG: pth:PTH_1661 pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit; PFAM: Pyruvate/ketoisovalerate oxidoreductase, catalytic domain.
 
 
 0.962
AEF94090.1
SMART: Iron hydrogenase, small subunit-like; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; TIGRFAM: Iron hydrogenase, subset; KEGG: drm:Dred_1654 hydrogenases, Fe-only; PFAM: Iron hydrogenase, large subunit, C-terminal; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; Ferredoxin; 4Fe-4S binding domain; Iron hydrogenase, small subunit-like.
   
 
 0.882
AEF94805.1
Phenylacetate--CoA ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).
 
    0.846
AEF95485.1
KEGG: drm:Dred_3188 indolepyruvate ferredoxin oxidoreductase; PFAM: Pyruvate/ketoisovalerate oxidoreductase, catalytic domain.
 
 
 0.841
moaC
Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
   
    0.614
AEF93361.1
PFAM: Amino acid-binding ACT; KEGG: drm:Dred_2883 amino acid-binding ACT domain-containing protein.
 
    0.590
AEF94808.1
Selenium metabolism protein YedF; KEGG: drm:Dred_1242 SirA family protein; TIGRFAM: SirA-related, selenium metabolism; PFAM: SirA-like; Belongs to the sulfur carrier protein TusA family.
       0.428
selD
Selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP.
       0.428
AEF94183.1
KEGG: toc:Toce_1202 2-oxoglutarate ferredoxin oxidoreductase, gamma subunit; PFAM: Pyruvate/ketoisovalerate oxidoreductase, catalytic domain.
  
 
 0.415
AEF93853.1
Glutamate synthase (NADPH); KEGG: dal:Dalk_2523 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S binding domain.
  
 
 0.413
Your Current Organism:
Desulfotomaculum nigrificans
NCBI taxonomy Id: 868595
Other names: D. nigrificans CO-1-SRB, Desulfotomaculum carboxydivorans CO-1-SRB, Desulfotomaculum carboxydivorans DSM 14880, Desulfotomaculum nigrificans CO-1-SRB
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