Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEF94837.1SMART: Iron hydrogenase, small subunit-like; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; TIGRFAM: Iron hydrogenase, subset; KEGG: pth:PTH_1377 hydrogenase subunit; PFAM: Iron hydrogenase, large subunit, C-terminal; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; 4Fe-4S binding domain; Iron hydrogenase, small subunit-like. (554 aa)    
Predicted Functional Partners:
AEF94836.1
NADH dehydrogenase (quinone); PFAM: NADH:ubiquinone oxidoreductase, 51kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; 4Fe-4S binding domain; KEGG: pth:PTH_1378 NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit; SMART: NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding.
 
 
 0.989
AEF94893.1
NADH dehydrogenase (quinone); PFAM: NADH:ubiquinone oxidoreductase, 51kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; 4Fe-4S binding domain; KEGG: hmo:HM1_1744 proton-translocating NADH-ubiquinone oxidoreductase, chain F; SMART: NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding.
 
 
 0.980
AEF94085.1
NADH dehydrogenase (quinone); PFAM: NADH:ubiquinone oxidoreductase, 51kDa subunit; Sucraseferredoxin-like; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; KEGG: drm:Dred_1652 NADH dehydrogenase (quinone); SMART: NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding.
 
 
 0.979
AEF94091.1
NADH dehydrogenase (quinone); PFAM: NADH:ubiquinone oxidoreductase, 51kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; 4Fe-4S binding domain; KEGG: drm:Dred_1655 NADH dehydrogenase (quinone); SMART: NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding.
 
 
 0.979
AEF93853.1
Glutamate synthase (NADPH); KEGG: dal:Dalk_2523 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S binding domain.
  
 
 0.969
AEF94090.1
SMART: Iron hydrogenase, small subunit-like; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; TIGRFAM: Iron hydrogenase, subset; KEGG: drm:Dred_1654 hydrogenases, Fe-only; PFAM: Iron hydrogenase, large subunit, C-terminal; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; Ferredoxin; 4Fe-4S binding domain; Iron hydrogenase, small subunit-like.
  
 
 0.963
AEF94528.1
PFAM: 4Fe-4S binding domain; Putative Fe-S cluster; KEGG: drm:Dred_2305 ferredoxin 2.
 
 
0.906
AEF94086.1
PFAM: NADH:ubiquinone oxidoreductase, 24kDa subunit; KEGG: drm:Dred_1653 NADH dehydrogenase (ubiquinone), 24 kDa subunit.
 
 0.895
AEF94092.1
KEGG: drm:Dred_1656 NADH dehydrogenase (ubiquinone), 24 kDa subunit; PFAM: NADH:ubiquinone oxidoreductase, 24kDa subunit.
 
 0.884
AEF94894.1
NADH dehydrogenase (quinone); KEGG: tjr:TherJR_0740 NADH-quinone oxidoreductase, E subunit; PFAM: NADH:ubiquinone oxidoreductase, 24kDa subunit.
  
 
 0.862
Your Current Organism:
Desulfotomaculum nigrificans
NCBI taxonomy Id: 868595
Other names: D. nigrificans CO-1-SRB, Desulfotomaculum carboxydivorans CO-1-SRB, Desulfotomaculum carboxydivorans DSM 14880, Desulfotomaculum nigrificans CO-1-SRB
Server load: low (10%) [HD]