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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (305 aa)    
Predicted Functional Partners:
AEF94840.1
PFAM: Homoserine dehydrogenase, catalytic; Aspartate/homoserine dehydrogenase, NAD-binding; Amino acid-binding ACT; KEGG: drm:Dred_1165 homoserine dehydrogenase.
  
 0.999
AEF93753.1
TIGRFAM: Threonine synthase; KEGG: drm:Dred_1379 threonine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit.
 
 0.998
AEF95316.1
TIGRFAM: Threonine synthase; KEGG: drm:Dred_0615 threonine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit.
  
 
 0.992
purM
TIGRFAM: Phosphoribosylformylglycinamidine cyclo-ligase; KEGG: drm:Dred_2364 phosphoribosylaminoimidazole synthetase; PFAM: AIR synthase-related protein, C-terminal; AIR synthase-related protein.
 
    
 0.906
AEF94453.1
Methionine synthase; KEGG: drm:Dred_2207 homocysteine S-methyltransferase; PFAM: Homocysteine S-methyltransferase; Pterin-binding; Methionine synthase, cobalamin (vitamin B12)-binding module, cap; Cobalamin (vitamin B12)-binding.
    
 0.890
AEF94838.1
KEGG: drm:Dred_1167 aspartate kinase; TIGRFAM: Aspartate kinase domain; Aspartate kinase, monofunctional class; PFAM: Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; Belongs to the aspartokinase family.
  
 
 0.882
AEF94380.1
TIGRFAM: Branched-chain amino acid aminotransferase II; KEGG: drm:Dred_2144 branched-chain amino acid aminotransferase; PFAM: Aminotransferase, class IV.
  
 
 0.850
AEF94841.1
UPF0735 ACT domain-containing protein; KEGG: drm:Dred_1164 hypothetical protein; HAMAP: Ligand-binding-predicted, ACT; PFAM: Amino acid-binding ACT; Belongs to the UPF0735 family.
 
     0.844
AEF93090.1
KEGG: drm:Dred_0192 serine O-acetyltransferase; TIGRFAM: Serine O-acetyltransferase.
     
 0.829
AEF94797.1
TIGRFAM: Serine dehydratase, alpha subunit; KEGG: drm:Dred_1253 L-serine dehydratase, iron-sulfur-dependent, alpha subunit; PFAM: Serine dehydratase-like, alpha subunit.
  
 
 0.825
Your Current Organism:
Desulfotomaculum nigrificans
NCBI taxonomy Id: 868595
Other names: D. nigrificans CO-1-SRB, Desulfotomaculum carboxydivorans CO-1-SRB, Desulfotomaculum carboxydivorans DSM 14880, Desulfotomaculum nigrificans CO-1-SRB
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