Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEF94843.1Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. (492 aa)    
Predicted Functional Partners:
AEF94961.1
TIGRFAM: Sporulation stage III, protein AD; KEGG: drm:Dred_1059 putative sporulation protein.
  
  
 0.929
AEF95442.1
TIGRFAM: Sporulation stage III, transcriptional regulator SpoIIID; KEGG: drm:Dred_3145 regulatory protein, DeoR.
  
  
 0.878
AEF94964.1
Stage III sporulation protein AA; KEGG: drm:Dred_1056 hypothetical protein; TIGRFAM: Sporulation stage III, protein AA; SMART: ATPase, AAA+ type, core.
  
  
 0.866
AEF95444.1
KEGG: drm:Dred_3147 SpoIID/LytB domain-containing protein; TIGRFAM: Sporulation stage II, protein D firmicutes; Sporulation stage II protein D, amidase enhancer LytB; PFAM: Sporulation stage II protein D, amidase enhancer LytB N-terminal.
  
  
 0.862
AEF94930.1
Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.847
AEF95286.1
Stage II sporulation protein R; KEGG: drm:Dred_0458 pro-sigma-E processing factor spoIIR; TIGRFAM: Sporulation stage II, protein R; PFAM: Sporulation stage II, protein R.
  
   
 0.847
AEF94962.1
TIGRFAM: Sporulation stage III, protein AC; KEGG: drm:Dred_1058 stage III sporulation AC family protein.
  
  
 0.845
AEF94958.1
KEGG: drm:Dred_1062 hypothetical protein.
  
  
 0.843
spoIIAB
Anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
  
 0.835
AEF94957.1
KEGG: drm:Dred_1063 hypothetical protein.
  
  
 0.824
Your Current Organism:
Desulfotomaculum nigrificans
NCBI taxonomy Id: 868595
Other names: D. nigrificans CO-1-SRB, Desulfotomaculum carboxydivorans CO-1-SRB, Desulfotomaculum carboxydivorans DSM 14880, Desulfotomaculum nigrificans CO-1-SRB
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